Figure 6.

A) SPECT-CT images of [^99mTc]Tc-tricarbonyl labelled RBC derived sEVs. B) Ex vivo biodistribution of ^99mTc-sEVs and [^99mTc]Tc-tricarbonyl injected iv. in male BALB/c mice about 2 h post injection (n = 3). Figures taken with permission from Varga et al. ⁸¹ C) In vivo biodistribution of ^99mTc-labelled goat milk derived sEVs injected in healthy female BALB/c mice via three different administration routes over time as indicated on the images. Figure adapted with permission from González et al. ⁸³.