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. 2021 Feb 5;13(2):220. doi: 10.3390/pharmaceutics13020220

Table 1.

Basic Properties of ALZ [16,17,18].

Molecular Weight pKa (Base), 25 °C LogP, 25 °C
265.3 4.2 3.1
Solubility, 37 °C (μg/mL)
pH 1.2 FeSSIFblk
(pH 5.0)
FeSSIF
(pH 5.0)
FaSSIFblk
(pH 6.5)
FaSSIF
(pH 6.5)
pH 7.4
184 1.1 6.1 0.85 1.9 0.75

Subscript “blk” means the removal of taurocholic acid and lecithin from simulated intestinal fluids.