. 2021 Feb 6;13(2):228. doi: 10.3390/pharmaceutics13020228

Table 4.

Values of kinetic parameters of drug release profiles before and after sterilization. The value of “n” of Korsmeyer–Peppas model (95% confidence level, CL), “K_c” of Heller and Baker model, and coefficients of determination (r²).

Drug Release	Korsmeyer-Peppas Model			Heller and Baker Model
Drug Release	Phase	r²	n (CL)	Phase	r²	K_c (days⁻¹)
Dx-MS	1	0.987	0.51 (0.46–0.56)	1	0.977	0.16
Dx-MS	2	0.995	2.79 (2.66–2.91)	2	0.991	0.34
Dx-MS, 25 kGy	1	0.993	0.46 (0.41–0.51)	1	0.995	0.30
Dx-MS, 25 kGy	2	0.996	2.06 (1.96–2.16)	1	0.995	0.30