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The PLC inhibitor U73122 blocks the antidepressant-like activity of the GSB-106 dipeptide and Amitriptyline in the forced swimming test in mice. *** p < 0.0001 statistical significance of differences compared to the “Control” group; ### p < 0.0001 statistical significance of differences compared to the “GSB-106” or “Amitriptyline” group (two-way ANOVA with Tukey’s post hoc test).
