The article titled “Longitudinal Monitoring of SARS-CoV-2 IgM and IgG Seropositivity to Detect COVID-19” (J Appl Lab Med 2020;5:908–20), published in the September 2020 issue of The Journal of Applied Laboratory Medicine, contains an error. In Table 5, the values for sensitivity and specificity should be repeated in every row for IgM, IgG, and IgM + IgG. The corrected table is provided below. The Journal regrets the error.
Table 5.
Positive and negative predictive values at various levels of disease prevalence.
| Prevalence (%) | IgM |
IgG |
IgM + IgG |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
| 20.0 | 89.5 | 99.6 | 98.1 | 97.4 | 94.7 | 99.1 | 96.5 | 98.7 | 100.0 | 98.7 | 95.1 | 100.0 |
| 7.5 | 89.5 | 99.6 | 94.4 | 99.2 | 94.7 | 99.1 | 89.9 | 99.6 | 100.0 | 98.7 | 86.3 | 100.0 |
| 4.3a | 89.5 | 99.6 | 90.4 | 99.5 | 94.7 | 99.1 | 83.2 | 99.8 | 100.0 | 98.7 | 77.7 | 100.0 |
| 2.2 | 89.5 | 99.6 | 82.1 | 99.8 | 94.7 | 99.1 | 70.8 | 99.9 | 100.0 | 98.7 | 63.1 | 100.0 |
| 1.1 | 89.5 | 99.6 | 69.4 | 99.9 | 94.7 | 99.1 | 54.5 | 99.9 | 100.0 | 98.7 | 45.8 | 100.0 |
| 0.5 | 89.5 | 99.6 | 53.0 | 99.9 | 94.7 | 99.1 | 37.4 | 100.0 | 100.0 | 98.7 | 29.6 | 100.0 |
| 0.3 | 89.5 | 99.6 | 36.0 | 100.0 | 94.7 | 99.1 | 22.9 | 100.0 | 100.0 | 98.7 | 17.3 | 100.0 |
Sensitivity and specificity is shown for seropositivity for samples ≥15 days after a confirmatory PCR test.
a
Estimated prevalence of SARS-CoV-2 in the high risk testing population at UC San Diego Health on April 16th, 2020.