Figure 3:

Panels A-F represent 3D-reconstructions of microcomputed-tomography specimens, A) Fgfr2^C342Y/C342Y, B) Fgfr2^C342Y/+, C) Fgfr2^+/Y394C, D) Fgfr2^+/S252W, E) Fgfr2^+/P253R and F) Fgfr2^+/+. Scale bars = 1.0 mm.

Panels G and H demonstrate box and whisker plots representing cartilage volume and airway volume, respectively. Center lines show the medians; box limits indicate the 25th and 75th percentiles; whiskers extend 1.5 times the interquartile range from the 25th and 75th percentiles; crosses represent sample means; data points are plotted as open circles.

* p < .05 vs Fgfr2^C342Y/C342Y

*** p < .001 vs Fgfr2^C342Y/C342Y

††† p < .001 vs Fgfr2^C342Y/+