Table 3.
STRING output of detected functional enrichments resulting from the submission of the complete dataset along with the associated log p-value for each protein.
| Term ID * | Term Description | Enrichment Score | Genes Mapped | Pathway Size | False Discovery (afc) |
|---|---|---|---|---|---|
| HSA-3928663 | EPHA-mediated growth cone collapse | 2.26367 | 17 | 28 | 0.00051 |
| CL:416 | Ephrin receptor activity, and Ephrin | 2.07704 | 20 | 23 | 0.00038 |
| CL:420 | Ephrin receptor activity, and Ephrin | 2.72701 | 13 | 16 | 0.00038 |
| IPR031328 | Ephrin | 3.36604 | 7 | 9 | 0.0049 |
| IPR019765 | Ephrin, conserved site | 3.36604 | 7 | 9 | 0.0049 |
| IPR001799 | Ephrin receptor-binding domain | 3.36604 | 7 | 9 | 0.0049 |
| IPR034252 | Ephrin-A ectodomain | 5.24701 | 4 | 6 | 0.0049 |
* Term IDs come from several functional enrichments. CL refers to local STRING network cluster; HSA to Reactome Pathways; IPR to INTERPRO Protein Domains and Features. An additional 37 “Reference publications” are omitted but can be easily retrieved by interested parties using data from Supplementary File 1, namely, columns “EntrezGeneSymbol” and the logged values of column “p-value”.