Table 5.
Details of the functional annotation clustering results with an enrichment score above five.
| Annotation Cluster | Enrichment Score | GO Term | Protein Count | p-Value | q-Value | |
|---|---|---|---|---|---|---|
| 1 | 14.3 | CC_GO:0005913 | Cell–cell adherens junction | 113 | 4.46 × 10−18 | 6.72 × 10−16 |
| MF_GO:0098641 | Cadherin binding involved in cell-cell adhesion | 98 | 1.59 × 10−14 | 3.49 × 10−12 | ||
| BP_GO:0098609 | Cell–cell adhesion | 90 | 2.46 × 10−12 | 9.64 × 10−10 | ||
| 2 | 6.5 | BP_GO:0038083 | Peptidyl-tyrosine autophosphorylation | 24 | 2.06 × 10−9 | 3.93 × 10−7 |
| MF_GO:0004715 | Nonmembrane spanning protein tyrosine kinase activity | 22 | 1.21 × 10−6 | 0.00009 | ||
| CC_GO:0031234 | Extrinsic component of cytoplasmic side of plasma membrane | 26 | 0.00001 | 0.0004 | ||
| 3 | 5.5 | BP_GO:0061621 | Canonical glycolysis | 17 | 1.65 × 10−7 | 0.00002 |
| BP_GO:0006096 | Glycolytic process | 18 | 3.70 × 10−6 | 0.0003 | ||
| BP_GO:0006094 | Gluconeogenesis | 19 | 0.00006 | 0.003 | ||
| 4 | 5.1 | BP_GO:0050919 | Negative chemotaxis | 21 | 1.37 × 10−8 | 2.17 × 10−6 |
| MF_GO:0045499 | Chemorepellent activity | 18 | 2.85 × 10−8 | 2.81 × 10−6 | ||
| BP_GO:0048843 | Negative regulation of axon extension involved in axon guidance | 15 | 8.89 × 10−6 | 0.0007 | ||
| MF_GO:0030215 | Semaphorin receptor binding | 13 | 0.00005 | 0.002 | ||
| BP_GO:0071526 | Semaphorin-plexin signaling pathway | 16 | 0.00006 | 0.003 | ||
| MF_GO:0038191 | Neuropilin binding | 10 | 0.0001 | 0.004 | ||
| BP_GO:0001755 | Neural crest cell migration | 16 | 0.003 | 0.07 | ||
| BP_GO:0008543 | Fibroblast growth factor receptor signaling pathway | 34 | 9.67 × 10−8 | 0.00001 | ||
| 5 | 5 | BP_GO:0048015 | Phosphatidylinositol-mediated signaling | 40 | 1.22 × 10−7 | 0.00002 |
| MF_GO:0046934 | Phosphatidylinositol-4,5-bisphosphate 3-kinase activity | 28 | 1.26 × 10−7 | 0.00001 | ||
| MF_GO:0005088 | Ras guanyl-nucleotide exchange factor activity | 41 | 2.52 × 10−7 | 0.00002 | ||
| BP_GO:0014066 | Regulation of phosphatidylinositol 3-kinase signaling | 32 | 3.27 × 10−7 | 0.00004 | ||
| BP_GO:0046854 | Phosphatidylinositol phosphorylation | 32 | 0.00003 | 0.002 | ||
| MF_GO:0005104 | Fibroblast growth factor receptor binding | 12 | 0.0002 | 0.006 | ||
| MF_GO:0016303 | 1-phosphatidylinositol-3-kinase activity | 13 | 0.03 | 0.35 | ||
| BP_GO:0036092 | Phosphatidylinositol-3-phosphate biosynthetic process | 14 | 0.04 | 0.46 | ||
Within GO term, CC, MF, and BP stand for cellular component, molecular function, and biological process, respectively.