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. 2020 Jul 10;2(7):384. doi: 10.1253/circrep.CR-66-0006

CORRIGENDUM: N-Terminal Pro-B-Type Natriuretic Peptide Is a Predictor of Chronic Kidney Disease in an Asian General Population ― The Ohasama Study ―

Shingo Nakayama, Michihiro Satoh ✉, Hirohito Metoki, Takahisa Murakami, Kei Asayama, Azusa Hara, Takuo Hirose, Ryusuke Inoue, Megumi Tsubota-Utsugi, Masahiro Kikuya, Takefumi Mori, Atsushi Hozawa, Koichi Node, Yutaka Imai, Takayoshi Ohkubo
PMCID: PMC7932809  PMID: 33704268

The authors apologize for the mistakes in the Results section. In Table 4, sex, current or ex-smoker, current or ex-drinker, hypercholesterolemia, diabetes mellitus, history of CVD, and antihypertensive medication should have been treated as binary variables coded as 1 or 0. However, the authors used the binary variables divided by 1-standard deviation. This error caused an underestimation of the hazard ratios of the binary variables. For example, the standard deviation of sex (men=1 and women=0) was calculated as 0.47, although it is an inappropriate calculation. Thus, the correct hazard ratio of men is calculated as follows: 0.80 [the value before correction](1/0.47)=0.62 [after correction]. All corrections are shown below.

Page 29, Table 4

Table 4.

HR for CKD Development of Covariates

Variables HR (95% CI) χ2 P-value
Sex (men=1, women=0) 0.62 (0.34–1.14) 2.37 0.12
Age (1-SD [10.2 years] increase) 1.22 (0.97–1.52) 2.95 0.086
BMI (1-SD [3.02 kg/m2] increase) 1.03 (0.88–1.21) 0.17 0.68
Current or ex-smoker (=1, non-smoker=0) 1.92 (1.05–3.49) 4.53 0.033
Current or ex-drinker (=1, non-drinker=0) 1.16 (0.79–1.70) 0.55 0.46
Hypercholesterolemia (=1, non-hypercholesterolemia=0) 0.83 (0.59–1.17) 1.10 0.29
Diabetes mellitus (=1, non-diabetes mellitus=0) 1.61 (0.94–2.77) 2.98 0.085
History of CVD (=1, no history of CVD=0) 0.93 (0.34–2.58) 0.017 0.90
Antihypertensive medication (=1, no antihypertensive medication=0) 1.02 (0.70–1.48) 0.0097 0.92
SBP (1-SD [=13.4-mmHg] increase) 1.06 (0.91–1.24) 0.57 0.45
eGFR (1-SD [=17.2-mL/min/1.73 m2] decrease) 3.18 (2.47–4.09) 81.1 <0.0001
lnNT-proBNP (1-SD [=0.87] increase) 1.26 (1.05–1.51) 5.97 0.015

We calculated the HR (95% CI) for CKD development per 1-SD increase in age, BMI, SBP, baseline eGFR, and lnNT-proBNP. For binary variables, the hazard ratio of code “1” (vs. “0”) is indicated. Abbreviations as in Table 1.


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