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[Preprint]. 2021 Mar 1:2021.02.25.21252447. [Version 1] doi: 10.1101/2021.02.25.21252447

Seroepidemiology of SARS-CoV-2 infections in an urban Nicaraguan population

Fredman González, Nadja A Vielot, Michael Sciaudone, Christian Toval-Ruíz, Lakshmanane Premkumar, Lester Gutierrez, Edwing Centeno Cuadra, Patricia Blandón, Aravinda M de Silva, Rebecca Rubinstein, Natalie Bowman, Sylvia Becker-Dreps, Filemon Bucardo
PMCID: PMC7941664  PMID: 33688687

ABSTRACT

In a Nicaraguan population-based cohort, SARS-CoV-2 seroprevalence was 34%, with higher prevalence in children compared to adults. Having a seropositive household member was associated with a two-fold probability of individual seropositivity, suggesting a role for household transmission. Co-morbidities and preventive behaviors were not associated with SARS-CoV-2 seroprevalence.

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