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. 2021 Mar 2;10:e63591. doi: 10.7554/eLife.63591

Figure 4. Task-induced shifts in cortex-wide functional connectivity.

Task-dependent functional connectivity profiles of the four IPL subregions with other coupling partners, compared to the respective other tasks. (a) Task-specific correlation between anterior (left) and posterior (right) IPL subregions and brain-wide cortical regions. All results are statistically significant at p < 0.05, tested against the null hypothesis of indistinguishable connectivity strength between a given IPL subregion and the rest of the brain across all three tasks. L-ant: left anterior IPL subregion; L-post: left posterior IPL subregion; R-ant: right anterior IPL subregion; R-post: right posterior IPL subregion. Dark gray: mutual connectivity target. (b) Task-specific connectivity profiles of the four IPL subregions with seven large-scale brain networks (Yeo et al., 2011). DAN: dorsal attention network. DMN: default mode network. FPN: fronto-parietal network. LIM: limbic network. VAN: ventral attention network. SMN: somatomotor network. VIS: visual network.

Figure 4.

Figure 4—figure supplement 1. Subregion-specific functional connectivity.

Figure 4—figure supplement 1.

The preferred connectivity between IPL subregions and brain-wide cortical regions identified task-specific coupling motifs of the four subregions. Large-scale brain networks were split into their left and right hemispheric parts. Functional connectivity was normalized per subregion and task. Anterior IPL subregions (top row) connect in a hemisphere specific way, while posterior IPL subregions (bottom row) connect in a more bilateral-symmetric way. LH/RH: left/right hemispheric network parts. See main text for details on the connectivity metric. Network acronyms as defined in the main text.