In the February 2000 issue of the AJNR, the article written by Rovaris et al (1) caught our attention. We admire the authors' use of neuropsychological tests for measuring cognitive functions in their study of multiple sclerosis. They seem to be aware of the sensitivity of neuropsychological tests in measuring cognition (2).
We also applaud the concept of incorporating comprehensive neuropsychological testing rather than using one or two for the research protocol.
To their credit, the authors not only cited research that confirmed a relationship with MR imaging, neuropsychological tests, and multiple sclerosis (3) but also data that did not (4).
We hope that the AJNR continues to publish research studies that incorporate neuroradiologic imaging and neuropsychological instruments.
References
- 1.Rovaris M, Filippi M, Minicucci L, et al. Cortical/subcortical disease burden and cognitive impairment in patients with multiple sclerosis. AJNR Am J Neuroradiol 2000;21:402-408 [PMC free article] [PubMed] [Google Scholar]
- 2.Reitan RM, Wolfson D. Traumatic Brain Injury: Pathophysiology and NeuropsychologicalEvaluation. . Tucson, AZ: Neuropsychology Press 1986;
- 3.Rao SM, Leo GJ, Haughton VM, St. Aubin-Faubert P, Bernardin L. Correlation of magnetic resonance imaging with neuropsychological testing in multiple sclerosis. Neurology 1989;39:161-166 [DOI] [PubMed] [Google Scholar]
- 4.Rovaris M, Filippi M, Falautano M, et al. Relation between MR abnormalities and patterns of cognitive impairment in multiple sclerosis. Neurology 1998;50:1601-1608 [DOI] [PubMed] [Google Scholar]