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. 2000 Dec 1;41(4):381–385. doi: 10.1186/BF03549628

Plasma Erythropoietin in Newborn Lambs

Erytropoietin i plasma hos nyfødte lam

Ø V Sjaastad 1,✉, A-K Egeli 2, A K Blom 1, T Framstad 2
PMCID: PMC7996410  PMID: 11234971

Abstract

In the present study early postnatal changes in erythropoietin (Epo) level and hemoglobin concentration in 8 lambs were examined. Plasma Epo was estimated by a monoclonal enzyme-immunoassay ( ELISA), developed for human Epo. In all the lambs, except one, Epo was low, or undetectable, immediately after birth. Within 6–12 h after birth, a marked increase in plasma Epo was found in 4 of the lambs. Within 3–7 days after birth, Epo was back to low levels. In the lamb with high Epo levels at birth, drastic decreases were observed during the next 6 h. There was no obvious correlation between the hemoglobin concentrations and the changes in plasma Epo.

Keywords: neonatal changes

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