There is an error in Table 1. The P value for BMI is incorrect. The P value for BMI should be <1x10-4.
Table 1. Phenotype characterisation of 1000 AWI-Gen participants and 4116 AADM participants.
| AWI-Gen | Replication cohort: AADM | |||
|---|---|---|---|---|
| Phenotype | High LDL-cholesterol (n = 500) | Low LDL-cholesterol (n = 500) | P value | (n = 4116) |
| Sex (%F) | 49.40% | 60.80% | 3x10-4 | 59.8% |
|
Age (years) median (IQR) |
51(45.00–56.00) | 50(45.00–55.00) | 0.19 | 51.00(42.00–60.00) |
|
BMI (kg/m2) median (IQR) |
25.94(18.22–29.51) | 20.73(19.04–23.27) | <1x10-4 | 25.90(22.55–29.71) |
|
Fasting serum glucose (mmol/L) median (IQR) |
5.08(4.96–5.53) | 4.60(4.19–5.05) | <1x10-4 | 7.31(4.61–8.56) |
|
LDL-cholesterol (mmol/L) median (IQR) |
4.21(3.93–4.61) | 0.90(0.71–1.01) | NA | 3.23(2.53–4.09) |
IQR = Interquartile range
Reference
- 1.Hayat M, Kerr R, Bentley AR, Rotimi CN, Raal FJ, Ramsay M (2020) Genetic associations between serum low LDL-cholesterol levels and variants in LDLR, APOB, PCSK9 and LDLRAP1 in African populations. PLoS ONE 15(2): e0229098. 10.1371/journal.pone.0229098 [DOI] [PMC free article] [PubMed] [Google Scholar]
