Figure 1.

Representation of the CC (A), DMC (B), and BDMC (C) plasma concentrations vs. time after the oral administration of a single dose of curcuminoids. Curcuminoid administration was performed either as free extract of curcuminoids (reference formulation, ▼, dotted line) or entrapped into three formulated systems: Nucaps developed formulation (NPZ-CC, ●, solid line) and two commercial formulations, a lecithin-based nanoparticle formulation (CPC, ▲, dashed line) and a cyclodextrin complex formulation (Curarti^®, ■, solid line).