Table 4.
Cox proportional hazard regression analysis in the 32 patients with NPC.
| Characteristics | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| Hazard Ratio (95%CI) | p-Value | Hazard Ratio (95%CI) | p-Value | |
| Gender (male) | 3.617 (0.758–17.272) | 0.107 | ||
| Smoking (smoking) | 0.328 (0.109–0.985) | 0.047 * | 0.224 (0.068–0.743) | 0.014 * |
| Alcohol (drinking) | 0.355 (0.106–1.187) | 0.093 | ||
| Tumor (T3–4) | 0.825 (0.275–2.477) | 0.732 | ||
| Lymph node (positive) | 1.707 (0.215–13.546) | 0.613 | ||
| Metastasis (positive) | 44.983 (4.001–505.715) | 0.002 * | 86.961 (6.936–1090.311) | 0.001 * |
| Stage (III–IV) | 27.608 (0.050–15205.502) | 0.303 | ||
| PD-L1 TPS (positive) | 2.162 (0.478–9.775) | 0.316 | ||
| PD-L1 CPS (positive) | 4.474 (0.580–34.500) | 0.151 | ||
| LMP1 (positive) | 1.026 (0.341–3.082) | 0.964 | ||
| sPD-L1 (≥0.1 ng/mL) | 1.293 (0.415–4.031) | 0.658 | ||
* p < 0.05. NPC: nasopharyngeal carcinoma, CI: confidence interval, LMP1: latent membrane protein 1, TPS: tumor proportion score, CPS: combined positive score, sPD-L1: soluble PD-L1.