Table 2.
CPET Data | HCM Group (N: 60 Patients) |
Healthy Controls (N: 60 Subjects) |
p-Values |
---|---|---|---|
Exercise time, minutes | 10.1 ± 2.0 | 10.8 ± 1.7 | NS |
Peak workload, watts | 116 ± 44 | 153 ± 42 | <0.001 |
Peak SBP, mm Hg | 143 ± 32 | 154 ± 17 | 0.034 |
Peak HR, % of predicted | 78 ± 11 | 83 ± 7 | NS |
VO2 AT, mL/kg/min | 17 ± 5 | 24 ± 7 | <0.001 |
Peak VO2, mL/kg/min | 28 ± 8 | 38 ± 8 | <0.001 |
Peak VO2, % of predicted | 63 ± 17 | 81 ± 13 | <0.001 |
Peak VO2 (Z-score) | −2.8 ± 1.2 | −0.9 ± 1.1 | <0.001 |
CP, mL/kg/min*mm Hg | 4101 ± 1840 | 5836 ± 1656 | <0.001 |
CP%, % of predicted*mm Hg | 9176 ± 3710 | 12,004 ± 2620 | <0.001 |
VE/VCO2 slope | 27.6 ± 4.8 | 23.4 ± 2.5 | <0.001 |
VE/VCO2 slope (Z score) | −0.2 ± 1.4 | −1.4 ± 0.7 | <0.001 |
R.E.R. | 1.15 ± 0.1 | 1.15 ± 0.1 | NS |
Data are expressed as mean ± SD. SBP: systolic blood pressure. HR: heart rate; VO2: oxygen uptake; AT: anaerobic threshold; CP: circulatory power; VE/VCO2 slope: relation between ventilation versus carbon dioxide production; R.E.R.: respiratory exchange ratio.