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Elsevier - PMC COVID-19 Collection logoLink to Elsevier - PMC COVID-19 Collection
. 2021 Mar 27;24:104004. doi: 10.1016/j.rinp.2021.104004

Modeling the dynamics of novel coronavirus (COVID-19) via stochastic epidemic model

Tahir Khan a, Gul Zaman a, Youssef El-Khatib b,
PMCID: PMC7999738  PMID: 33816091

Abstract

In this article we propose a stochastic model to discuss the dynamics of novel corona virus disease. We formulate the model to study the long run behavior in varying population environment. For this purposes we divided the total human population into three epidemiological compartments: the susceptible, covid-19 infected, recovered and recovered along with one class of reservoir. The existence and uniqueness of the newly formulated model will be studied to show the well-possedness of the model. Moreover, we investigate the extinction analysis as well as the persistence analysis to find the disease extinction and disease persistence conditions. At the end we perform simulation to justify the investigation of analytical work with the help of graphical representations.

Keywords: COVID-19, Stochastic model, Existence and uniqueness analysis, Extinction as well as persistence, Simulation

Introduction

Corona viruses consist of a wide family of viruses This can cause human diseases, ranging from the popular Severe Acute Respiratory Syndrome (SARS) colds. In the previous two decade, two epidemics of corona virus have been reported. The one called SARS caused a large-scale epidemic devastation in China and targeting two dozen countries with reported 8000 cases along with 800 deaths. The other epidemic was Middle East Respiratory Syndrome Coronavirus (MERS), which initially reported in the Kingdom of Saudi Arabia and consequently 2,500 number of individuals infected with 800 deaths [1], [2], [3], [4].

In December 2019, a serious outbreak of respiratory disease started in Wuhan city, China [5], [4]. The causative agent is the novel corona virus that was detected in early January and isolated from one single patient. The pandemic of the novel corona virus infected approximately 21,101,574 confirmed cases, including 758,025 deaths till 14 August, 2020. The World Health Organization reveal it as a Public Health Emergency of International Concern. This new virus appears to be extremely infectious and has spread rapidly across the globe making it a global pandemic. The potential spreading of these disease become pandemic worldwide and therefore seems to be a very serious public health risk. The COVID-19 infection normal symptoms including fever, cough, breathing, fatigue and difficulties like (MERS-CoV) and (SARS-CoV) infection.

The literature reveals that the novel corona virus disease (COVID-2019) has been identified as a global issue and therefore got the attention of many researches. Many mathematician as well as biologists performed experiments to forecast the future possible progression via various mathematical models [6]. A variety of mathematical studies for the dynamics of novel corona virus outbreak as well as other infectious diseases have already been carried out, see for detail [7], [8], [9], [10], [11], [12], [13], [14], [15]. While there is an onset of epidemic, human-to–human transmission occur resulting in the rise of cases of corona virus disease worldwide. Due to limited resources, the most important thing for health care providers becomes the forecasting about the disease. It could be also noted to the best of our knowledged from the resent literature that most of the deterministic modeling approach were used for the dynamics of novel corona virus while modeling the transmission dynamics of infectious disease stochastic differential equations model is more appropriate, for example see [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28]. Similarly according to the characteristic of the novel corona virus disease the stochastic modeling approach is more suitable then deterministic one.

In this study, we propose and analyze a stochastic epidemic compartmental model for covid-19 according to the characteristics of novel corona virus disease. It could be noted form the spreading of the novel corona virus disease that the ratio of transmission is different from place to place and therefore the random fluctuation of the environment is taken to be in the transmission rate and so distributed. We formulated the model with the fact that adding the noise term in the transmission rate. Once formulate the model we discuss the existence analysis and uniqueness by using the stochastic Lyapnov function theory to investigate the well possedness of the proposed problem. We also find the condition for the extinction and persistence by discussing the extinction and persistence analysis. At the end we use the well known purely numerical technique of stochastic Euler Maruyama technique to perform the numerical simulation and show the feasibility of the analytical work graphically.

Model formulation

We formulate a stochastic model for the dynamics of novel corona virus disease in this section. Without the direct representation of the model, we put some assumptions.

  • a.  All variables, constants as well as parameters of the model are non-negative.

  • b.  The total human population is represented by N1(t) and consequently divided into three epidemiological groups of susceptible, infected and recovered population.

  • c.  It could be noted that the corona pandemic rises from the human to human contact worldwide and the stochastic behaviors of population groups of the proposed problem are supposed to be driven by the same source or randomness B(t). This can be seen as the model proposes that variations in population groups are linked to the same source of information represented by the Brownian motion filtration F=(Ft)t[,T], where Ftσ(B(t)) is the σ-algebra generated by B(t) leads to the fact that any change in one population group has directly an impact on the other groups. Therefore the random fluctuation of the environment are taken to be in the transmission rate, such that β1β1+η1B˙(t) and β2β2+η2B˙(t). Here B(t) symbolize the standard Brownian motion, while η1 and η2 are white noise intensities. Clearly the Brownian motion obey the property of B(0)=0 and η12,η22>0.

Thus keeping in view (2019-nCoV) characteristics along with the above assumptions, we explore the problem in term of the nonlinear model:

ds(t)=(Π-β1i(t)+β2w(t)+ds(t))dt-η1s(t)i(t)dB(t)-η2s(t)w(t)dB(t),di(t)=(β1i(t)+β2w(t))s(t)-(d+d1+σ)i(t)dt+η1s(t)i(t)dB(t)+η2s(t)w(t)dB(t),dr(t)=(σi(t)-dr(t))dt,dw(t)=(αi(t)-ηw(t))dt, (1)

where the new born rate is Π, while β1 and β2 are assumed to be the two transmission routs i.e., from infected individuals and reservoir. We also denote the natural death by d and the disease death by d1. Moreover, it is assumed that σ is the recovery of the infected population. Finally the rate of virus contributing to the seafood market is taken to be α, while η is the removal proportion of the virus.

Clearly the proposed model (1) reduces to its associated deterministic form, if the intensities of white noise η1=η2=0. In addition the associated deterministic model having two type of equilibria: disease free and endemic equilibrium respectively denoted by e0=(s0,0,0,0) and e=(s,i,r,w), where

s0=Πd,sh=(d+d1+σ)ηβ1η+β2α,i=ηd(R0-1)(σ+d+d1)β1ση+β2σα+β1dη+β2dα+β1d1η+β2d1α,r=σdih,w=αη(R0-1)(σ+d+d1)β1ση+β2σα+β1dη+β2dα+β1d1η+β2d1α, (2)

where R0 is the threshold parameter or also known the basic reproductive number of the associated deterministic model of system (1). To find this quantity, let X=(i,w)T, than

dXdt=F-V, (3)

where

F=β1i(t)s(t)+β2w(t)s(t)0,V=(d+d1+σ)i(t)ηw(t)-αi(t). (4)

Calculating the Jacobian of the above matrices F and V around the disease free state e0=(s0,0,0,0), we may arrives at

F=β1s0β2s000,V=d+d1+σ0-αη. (5)

The threshold quantity is the spectral radius of the matrix, H=FV-1, and so consequently having the following expression is given by

R0=Πβ1(d+d1+σ)d+αΠβ2(d+d1+σ)η. (6)

Existence and uniqueness analysis

The current section is dedicated to find the existence analysis and uniqueness analysis of the stochastic model (1).

The Itô formula presented in the next lemma will be very useful in getting our results. It is a special case of the Multidimensional Itô formula that can be found in many books on stochastic calculus e.g. [29].

Lemma 1

Let a=(a1,,an) and b=(b1,,bn) denote two n-dimensional square-integrable adapted processes. We consider the process X=(X1,,Xn) , where for k{1,,n},Xk is driven by the stochastic differential equation

dXk(t)=ak(t)dt+bk(t)dB(t),Xk(0)R.

Given a function F twice continuously differentiable from Rn to R , then we have

dFXt=k=1nFxkXtdXkt+k,l=1n122FxkxlXtdXkt,dXlt,

where

dXkt,dXlt=bktbltdt,

since dBt,dBt=dt and dt,dBt=dBt,dt=dt,dt=0.

We have the following results to discuss the properties of existence and uniqueness.

Theorem 2

For every initial sizes (s(0),i(0),r(0),w(0)) in R+4 , the model (1) solution i.e., (s(t),i(t),r(t),w(t)) is unique and remains in R+4 almost surely (a.s).

Proof

We first show existence and uniqueness of local positive solution then we prove that the local solution is global. Our proof is based on results from [30], [31], [32]. In the following, we adopt the same method used in Lei et al., [33] and more recently in [34]. So in view of the properties of locally Lipschitz continuity for the proposed model (1) holds, therefore, we assume that if τe is the explosion time then the solution (s,i,r,w) for t in [0,τe) along with non-negative initial population sizes (s(0),i(0),r(0),w(0)) in R+4 is unique local. Further to perform that the solution is global, we need to investigate the axioms of τe= a.s. For this we assume that κ0 a positive constant i.e., κ00 be sufficiently large such that 1κ0<(s(0),i(0),r(0),w(0))<κ0. The stopping time for each integer κκ0 is define to be

τk=inft[0,τe):min(s(t),i(t),r(t),w(t))1kormax(s(t),i(t),r(t),w(t)). (7)

Let us assume that ϕ is the null set, then setting =infϕ. It could be noted that the increasing of τk depends on the value of k and consequently increasing if the value of k is increasing i.e., τk rises with k approaches . The substitution of lim=τ as t along with the investigation of τ= a.s leads to (s(t),i(t),r(t),w(t))R+4, non-negative t a.s. It clearly shows that only we need to prove that τe=. Thus we assume that there are two constants such that T>0 and ε(0,1), such that

P{τT}>ε. (8)

So k1k0 is an integer that

P{τkT}ε,foreverykk1. (9)

Let us assume that N=N1+N2, where N1=s+i+r and N2=w then for any tτk, we may arrives to the following assertions

dN1(t)=Π-(s(t)+i(t)+r(t))d-d1r(t)dt. (10)

Using some algebraic manipulation the above Eq. (10) ultimately takes the following form

dN1(t)Π-N1(t)ddt. (11)

Solving Eq. (11), we obtain the following assertion is given by

N1(t)Πd,ifN1(0)Πd,N1(0),ifN1(0)>Πd. (12)

Similarly the temporal differentiation of N2(t) takes the following form

dN2(t)=αi(t)-ηw(t)dt. (13)

The use Eq. (12) in Eq. (13) with little re-arrangement gives the solution is represented by

N2(t)αΠd,ifN2(0)αΠd,N2(0),ifN2(0)>αΠd. (14)

Thus the combination of Eq. (12) and Eq. (14) lead to the following assertion is symbolized by

N(t)ΠdifN1(0)Πd,N1(0)ifN1(0)>Πd,αΠdifN2(0)αΠd,N2(0)ifN2(0)>αΠd.M. (15)

Moreover, let HC2, i.e., H:R+4R+ define by

H(s,i,r,w)=s+i+r+w-4-log(s+i+r+w). (16)

It could be noted from the above Eq. (16) that H is non-negative. Thus for k0k and 0T, we apply the ito formula which lead to the following assertion

dH(s,i,r,w)=LH(s,i,r,w)+(i-s)η1+η2widB(t), (17)

where

LH(s,i,r,w)=(1-1/s)(Π-β1si-β2sw-ds)+12s2(ds)2+(1-1/i)(β1si+β2sw-(d+d1+σ)i)+12i2(di)2+(1-1/r)(σi-dr)+(1-1/w)(αi-ηw). (18)

Simplifying and the use of algebraic manipulation gives the following

LH(s,i,r,w)=Π+2d+d1+σ+η-ds-Π/s+12(η12i2+η22w2)-(d+d1)i-β2sw/i+12η12s2-dr-σi/r+αi-ηw-αi/w, (19)

which implies that

LH(s,i,r,w)Π+2d+d1+σ+η+12(η12s2+η12i2+η22w2)+αi. (20)

Let ρ=maxη12,η22 then the above equation i.e., Eq. (20) can be re-written as

LH(s,i,r,w)Π+2d+d1+σ+η+12ρ(s2+i2+w2)+αi. (21)

It is very much clear that a2+b2+c2(a+b+c)2, so Eq. (21) may be expressed in the following form

LH(s,i,r,w)Π+2d+d1+σ+η+12ρ(s+i+w)2+αi. (22)

Furthermore it could be noted from the fact that N=N1+N2, therefore making use of the Eq. (15) in Eq. (23) leads to the assertion is give by

LH(s,i,r,w)Π+2d+d1+σ+η+12ρM2+αMK. (23)

Hence

EH(s(τkT),i(τkT),r(τkT),w(τkT))H(s(0),i(0),r(0),w(0))+E0τkTKdt,H(s(0),i(0),r(0),w(0))+TK. (24)

Set Ωk=Tτk for k1k. As a result, Eq. (8) reads P(Ωk). So for all ωΩk, there is at least one s(ω,τk), i(ω,τk),r(ω,τk),w(ω,τk) exists, which will be equal to 1k or k. So H is not less then 1k+logk-1 or -logk+k-1. Then

HE1k-1+logk-logk-1+k. (25)

Using Eq. (8) and Eq. (24), we write

H(s(0),i(0),r(0),w(0))+TKE1Ω(ω)Hs(τk),i(τk,r(τk),w(τk)),logk+1k-1(-logk+k-1), (26)

where the notion 1Ω(ω) is used for the indicator function of Ω. Let k then it contradict that >Hs(0),i(0),r(0),w(0)+MT=, which ultimately implies that τ= a.s. □

Remark 1

It could be noted from the existence analysis that for any initial population sizes (s(0),i(0),r(0),w(0))R+4, the unique global solution (s(t),i(t),r(t),w(t))R+4 exists almost surly (a.s) for the proposed problem (1), therefore

d(s+i+r)Π-(s+i+r)ddt (27)

and

dwαi-ηwdt (28)

Solving Eq. (27), (28) with some manipulation we get the following assertions

limt(s+i+r)Π/dandlimtwαΠ/ηd. (29)

Hence the feasible region for the proposed problem (1) is given by the following bounded set

Ω=(s,i,r,w)R+4:s>0,i,r,w0:(s+i+r)Π/d,wαΠ/ηd (30)

is invariant positively subjected to the proposed system (1).

Theorem 3

The solutions (s,i,r,w) of the proposed system (1) are positive for (s(0),i(0),

r(0),w(0)) R+4 a.s for t>0.

Proof

We suppose that the solutions of stochastic corona model (1) exists in the interval [0,+). To solve the first and second equations of model (1), as in [35] we consider the process (ξ(t))tR+ defined by the SDE

dξ(t)=a(t)ξ(t)dt+b(t)ξ(t)dB(t),ξ(0)=1, (31)

where (a(t))tR+ and (b(t))tR+ are two stochastic processes satisfying the required conditions to insure a solution of (31) as follows

ξ(t)=exp0ta(u)-b2(u)2du+0tb(u)dB(u),tR+. (32)

Then the variation of constants method will be utilized to assume that the solution of the first equation of our model can be written as s(t)=y(t)ξ(t), with y(0)s(0),a(t)-β1i(t)+β2w(t)+d, and b(t)-η1i(t)-η2w(t). Then y(t) can be obtained using the below integration by parts for stochastic processes

dy(t)=d(ξ-1(t)s(t))=ξ-1(t)ds(t)+s(t)dξ-1(t)+[dξ-1(t),ds(t)].

Here dξ-1(t) is calculated using Ito formula applied to f(ξ(t))=1ξ(t). The solution of first equation of model (1) is then given by

s(t)=s(0)+Π0tξ-1(u)duξ(t),tR+.

The second equation of stochastic corona model (1) can be also obtained using the same methodology as above but with i(t)=z(t)ξ(t), with z(0)s(0),a(t)β1s(t)-(d+d1+σ), and b(t)η1s(t). The solution of second equation of model (1) is then given by

i(t)=i(0)+0t(β2-b(u)η2)w(u)s(u)ξ-1(u)du+0tη2s(u)w(u)ξ-1(u)dB(u)ξ(t),

where tR+. Similarly it is not tedious to show that r(t)0 and w(t)0. Hence the solutions of the model (1) are positive. □

Extinction and persistence analysis

The current section is devoted to discuss the extinction as well as persistence analysis. We find the condition that how the disease extinct and persist in a population. Before we are going in the detail analysis, we introduce some preliminaries results and notation. Let us assume that the mean value of γ(t) is given by

γ(t)=1t0tγ(x)dx, (33)

and therefore the disease persist if liminfi(t) and liminfw(t) whenever t approaches are positive. Moreover, we assume that the parameter R0S is defined to be the basic reproductive parameter for the corona system (1) is as

R0S=Πβ1dd+d1+σ+Π22d2(η12+η22)+αΠβ2ηd+d1+σ+Π22d2(η12+η22). (34)

Moreover, the proposed problem (1) persistent if it satisfy the following conditions

limtinf0ti(x)dx>0,a.s., (35)

and

limtinf0tw(x)dx>0,a.s. (36)

Extinction analysis

To discuss the analysis of extinction and looking for the conditions that how the disease will be extinct from the community, we have the following theorems.

Theorem 4

Since (s,i,r,w) is the solution of system (1) and (s(0),i(0),r(0),w(0))Ω is the initial sizes of the populations, then

limt(logi(t)/t)<0andlimt(logw(t)/t)<0,a.s., (37)

or consequently we can write that i(t)0 , r(t)0 and w(t)0 exponentially a.s., i.e., the infection of novel corona virus disease will dies surly, if the following conditions are satisfied

R0S<1anddη(β1η+β2d)>Π(η12+η22)+αη22Π. (38)

Moreover,

imts(t)=s0,limti(t)=i0,limtr(t)=r0,limtw(t)=w0. (39)

Proof

We follow the same methodology as reported in Lei et al., [33], therefore integrating both sides of system (1), we get the following system of equations

0tds(x)=Πt-0tβ1i(x)+β2w(x)+ds(x)dx-0tη1s(x)i(x)+η2s(x)w(x)dB(x),0tdi(x)=0t(β1i(x)+β2w(x))s(x)-(d+d1+σ)i(x)dx+0tη1s(x)i(x)+η2s(x)w(x)dB(x),0tdr(x)=0t(σi(x)-dr(x))dx,0tdw(x)=0t(αi(x)-ηw(x))dx. (40)

Using the formula is given in Eq. (33) with little re-arrangement, the above Eq. (40) looks like

s(t)-s(0)t=Π-β1i(t)s(t)-β2w(t)s(t)-s(t)d-η1/t0ts(x)i(x)dB(x)-η2/t0ts(x)w(x)dB(x),i(t)-i(0)t=β1i(t)s(t)+β2w(t)s(t)-(d+d1+σ)i(t)+η1/t0t(s(x)i(x)dB(x)+η2/t0ts(x)w(x))dB(x),r(t)-r(0)t=σi(t)-dr(t),w(t)-w(0)t=αi(t)-ηw(t).

Adding first and second equation of the above system and making use of ψ1(t)=-1/ts(t)-s(0)t+i(t)-i(0)t, we obtain

s(t)=Π/d-(d+d1+σ)i(t)/d+ψ1(t). (41)

Similarly the addition of first, second and third equation of the above system gives the following expression

w(t)=Π/η-(d+d1+σ-α)i(t)/η+ψ2(t), (42)

where ψ2(t)=-1/ts(t)-s(0)t+i(t)-i(0)t+w(t)-w(0)t. Clearly if t approaches to , then limψ1(t) and limψ2(t) tend to zero. Moreover the application of Ito^ formula to the 2nd equation of system (1) leads to the following equation

dlogi(t)=β1s+β2w-(d+d1+σ)-η12s2/2-η22w2/2dt+(η1s+η2w)dB(t). (43)

Integrating both side of the above Eq. (43) with limit from 0 to t and then dividing the resultant expression by t we get the following assertion

1t(logi(t)-logi(0))=β1s+β2w-(d+d1+σ)-η12s2/2-η22w2/2+η1/t0tsdB(t)+η2/t0twdB(t). (44)

It is clear from Eq. (33) that a2(x)a(x)2, therefore the above Eq. (44) may take the following form

1t(logi(t)-logi(0))β1s+β2w-(d+d1+σ)-η12s2/2-η22w2/2+η1/t0tsdB(t)+η2/t0twdB(t). (45)

Using the notion M1(t)=η10tsdB(t) and M2(t)=η20twdB(t) for the local continuous martingale in Eq. (45), then the above inequality looks like

1t(logi(t)-logi(0))β1s+wβ2-(d1+d+σ)-η12s2/2-η22w2/2+M1(t)/t+M2(t)/t. (46)

Plugging Eq. (41), (42) in the above Eq. (46) lead to the assertion is given by

1tlogi(t)-logi(0)β1Π/d-(d+d1+σ)i(t)/d+ψ1(t)+β2Π/η-(d+d1+σ-α)i(t)/η+ψ2(t)-(d+d1+σ)-η12Π/d-(d+d1+σ)i(t)/d+ψ1(t)2/2-η22Π/η-(d+d1+σ-α)i(t)/η+ψ2(t)2/2+M1(t)/t+M2(t)/t,

which implies that

1tlogi(t)-logi(0)-d+d1+σ+η12Π22d2+η22Π22η21-R0S-d+d1+σdη(β1η+β2d)-Π(η12+η22)+αη22Πi(t)+Φ(t)+M1(t)/t+M2(t)/t, (47)

where

Φ(t)=β1ψ1(t)+β2ψ2(t)-η12ψ12(t)/2+η12(d+d1+σ)ψ1(t)i(t)/d-η12Πψ1(t)/d-η22ψ2(t)-η22(d+d1+σ-α)ψ2(t)i(t)/d-η22Πψ2(t)/η. (48)

Following the strong law of large number for the local continues martingales that limsupM1(t)/t=0,limsupM2(t)/t=0 and limΦ(t)=0 as t approaches a.s. Moreover, Eq. (47) implies that

1tlogi(t)-logi(0)-d+d1+σ+η12Π22d2+η22Π22η21-R0S-d+d1+σdη(β1η+β2d)-Π(η12+η22)+αη22Πi(t). (49)

If R0S<1 and dη(β1η+β2d)>Π(η12+η22)+αη22Π, then we may write the above inequality in the following form

limt1tlogi(t)-d+d1+σ+η12Π22d2+η22Π22η21-R0S-d+d1+σdη(β1η+β2d)-Π(η12+η22)i(t)+αη22Π<0a.s. (50)

Alternatively Eq. (50) shows that limi(t)=0 as t, which implies that limi(t)=0 as t. Also we know that

r(t)=1dσi(t)-r(t)-r(0)tandw(t)=1ηαi(t)-w(t)-w(0)t. (51)

It could be noted from limi(t)=0 and the above Eq. (51) that limr(t)=0 and limw(t)=0 as t. Using all these data i.e., limi(t)=0,limr(t)=0 and limw(t)=0, Eq. (41) implies that lims(t)=Π/d a.s as t approaches . Thus it could be concluded that the extinction of the disease depend on the choice of parameters R0S<1 as well as dη(β1η+β2d)>Π(η12+η22)+αη22Π, and if these conditions holds the novel corona virus disease will extinct from the community. □

Persistence analysis

We discuss the analysis of persistence in this subsection. We find that how the novel corona virus disease will persist in the community and therefore for analysis of persistence the following theorems are described.

Theorem 5

For any initial sizes (s(0),i(0),r(0),w(0))Ω , the solution (s,i,r,w) of system (1) satisfying the property is given by

i2limtinfi(t)limtsupi(t)i1a.s., (52)

and

w2limtinfw(t)limtsupw(t)w1a.s. (53)

In Eq. (52), (53) , the value of i1,i2,w1 and w2 are defined by

i1=d+d1+σ+η12Π22d2+η22Π22η2R0S-1d+d1+σdη(β1η+β2d)-Π(η12+η22)+αη22Π,i2=dηd+d1+σ+η12Π22d2+η22Π22η2R0S-1d+d1+σ{β1η+β2d(1-α)},w1=αηd+d1+σ+η12Π22d2+η22Π22η2R0S-1d+d1+σdη(β1η+β2d)-Π(η12+η22)+αη22Π,w2=αdd+d1+σ+η12Π22d2+η22Π22η2R0S-1d+d1+σ{β1η+β2d(1-α)}, (54)

if the following conditions are satisfied

R0S<1anddη(β1η+β2d)>Π(η12+η22)+αη22Π. (55)

Proof

By following the work of Lei et al., [33], it could be noted from Eq. (47) that

1tlogi(t)-logi(0)d+d1+σ+η12Π22d2+η22Π22η2R0S-1-d+d1+σdη(β1η+β2d)-Π(η12+η22)+αη22Πi(t)+Φ(t)+M1(t)/t+M2(t)/t. (56)

Consequently the above inequality can be written as

i(t)d+d1+σ+η12Π22d2+η22Π22η2R0S-1d+d1+σdη(β1η+β2d)-Π(η12+η22)+αη22Π+Φ(t)+1tM1(t)+M2(t)+logi(0)-logi(t)d+d1+σdη(β1η+β2d)-Π(η12+η22)+αη22Π. (57)

Taking the supremum as well as lim of both side, we get the following assertion is given by

limtsupi(t)d+d1+σ+η12Π22d2+η22Π22η2R0S-1d+d1+σdη(β1η+β2d)-Π(η12+η22)+αη22Π=i1. (58)

On the other hand the substitution of Eq. (15), (41), (42) in Eq. (44), leads to the expression is give by

1t(logi(t)-logi(0))β1Πd-(d+d1+σ)i(t)/d+ψ1(t)+β2Πη-(d+d1+σ-α)i(t)/η+ψ2(t)-(d+d1+σ)-η12Π2/2d2-η22α2Π2/2η2d2+ψ2(t)+ψ1(t)+M2(t)+M1(t)t. (59)

We assume that η>d, then the above inequality may take the following form

1t(logi(t)-logi(0))β1Πd-(d+d1+σ)i(t)/d+ψ1(t)+β2Πη-(d+d1-α+σ)i(t)/η+ψ2(t)-(d+d1+σ)-η12Π2/2d2-η22Π2/2η2+ψ1(t)+ψ2(t)+M1(t)+M2(t)t. (60)

Using some algebraic manipulation and the parameter R0S as stated in Eq. (34) we arrive the following

1t(logi(t)-logi(0))(d+d1+σ)+η12Π22d2+η22Π22η2-1dη(d+d1+σ){β1η+β2d(1-α)}i(t)+ψ2(t)+ψ1(t)+M2(t)+M1(t)t. (61)

Solving the above inequality for i(t) and then taking lim with inferior of both side we get

limtinfi(t)dηd+d1+σ+η12Π22d2+η22Π22η2R0S-1d+d1+σ{β1η+β2d(1-α)}=i2 (62)

Combining Eq. (58), (62) we get

i2limtinfi(t)limtsupi(t)i1a.s. (63)

Moreover from the third equation of system (40) one may write

1tlogw(t)-logw(0)=αi(t)-ηw(t). (64)

which implies that

limtsupw(t)αηd+d1+σ+η12Π22d2+η22Π22η2R0S-1d+d1+σdη(β1η+β2d)-Π(η12+η22)+αη22Π=w1. (65)

Similarly it can be written as

limtinfw(t)αdd+d1+σ+η12Π22d2+η22Π22η2R0S-1d+d1+σ{β1η+β2d(1-α)}=w2. (66)

Thus from Eq. (66), (67) we may write

w2limtinfw(t)limtsupw(t)w1a.s. (67)

 □

Numerical simulation

The section is devoted to perform the simulation analysis of the novel corona virus model (1). The purposes of numerical simulation is to verify the analytical findings.

We first give a short overview on simulating stochastic differential equations-SDEs 1 since our model system in (1) is driven by SDEs. Consider a one dimensional stochastic process X(Xt)t[0,T] driven by the following SDE

dX(t)=a(t,X(t))dt+b(t,X(t))dB(t),X(0)=x. (68)

The aim is to reproduce the evolution of X(t) over a continuous time period. It is possible to generate a sample of X(t) at a given time t utilizing the SDE solution in case (68) is solved. Nonetheless, in general this can be done by simulating the SDE. As for deterministic differential equations, a discretization X~ of the SDE at a finite number of points is needed. For seek of simplification, we use the denotations X~k instead of X~(kΔt) and Bk instead of B(kΔt), then a discretization of (68) can be given by

X~Δt,X~Δt,,X~NΔt

with N is the number of time steps and Δt:=TN is the time step. Using Itô-Taylor expansion, we can get several discretization methods such as Euler–Maruyama, Milstein, or Runge–Kutta. Despite that Milstein and Runge–Kutta have higher order in discretization compared to Euler–Maruyama scheme, they could be more expensive on computation since first and second derivatives of the volatility term ”b” are required. We use then the well known numerical scheme of stochastic Euler–Maruyama technique to perform the investigation of our analytical results graphically. To obtain a discretized trajectory of X(t) form the SDE (68) using Euler–Maruyama scheme

  • 1.

    simulate ΔBk as normally distributed random variable N(0,Δt)

  • 2.
    set X~0X0=x and evaluate X~k+1 using
    X~k+1=X~k+a(kΔt,X~k)Δt+b(kΔt,X~k)ΔBk, (69)

for k=0,,N-1. Notice that ΔBk=Bk+1-Bk. We will omit, from now on, the use of the symbol ~ for discretized version of a given SDE.

The application of stochastic Euler Maruyama technique to the model (1) gives the system

sk+1-sk=Π-β1iksk-β2wksk-dskΔt-η1iksk+η2wkskΔBk,ik+1-ik=β1iksk+β2wksk-d+d1+σikΔt+η1iksk+η2wkskΔBk,rk+1-rk=σik-drkΔt,wk+1-wk=αik-ηwkΔt. (70)

Consequently the above system (70) can be re-written as

sk+1=sk+Π-β1iksk-β2wksk-dskΔt-η1iksk+η2wkskΔBk,ik+1=ik+β1iksk+β2wksk-d+d1+σikΔt+η1iksk+η2wkskΔBk,rk+1=rk+σik-drkΔt,wk+1=wk+αik-ηwkΔt. (71)

Moreover we code the above algorithm via Matlab software along with the biological feasible value of parameters and initial sizes of populations to show the stochastic process influence with the help of graphs. We use two different set of parameters values i.e., one for the extinction analysis and one for the persistence analysis to verify the analytical findings. Let S={Π,β1,β2,η1,η2,d,d1,σ,α,η} be the set of parameter whose values are assumed to perform the verification of extinction analysis. The choice of parameters value in the case of extinction analysis are as: Π=0.5, β1=0.045,β2=0.15,η1=0.5,η2=0.1, d=0.2,d1=0.028,σ=0.2,α=0.2,η=0.25, while the value for the analysis of persistence are assumed as: Π=0.5, β1=0.6,β2=0.15,η1=0.4,η2=0.3, d=0.015,d1=0.18,σ=0.001,α=0.1,η=0.12. After executing with all these data we obtain the results as given in   Fig. 1 . The different trajectories of   Fig. 1a demonstrate the susceptible dynamics, covid-19 infected, recovered and reservoir, which shows the extinction of the novel corona virus disease as shown in Theorem 4.1. This clearly splash that the susceptible population exist always while the remaining will vanishes after some time. Similarly the analysis of persistent are shown in   Fig. 1b, which verify the analytical result as discussed in Theorem 4.2. In this case the solution trajectories of the various compartment of susceptible, infected, recovered and reservoir show that the disease persist as shown in   Fig. 1b. Moreover, we also observe the influence of noise on the disease transmission that the increasing of noise intensity is directly proportional to the disease transmission while inversely proportional to the persistence of the disease.

Fig. 1.

Fig. 1

The dynamics of the novel corona virus model (1) against the relative parameters as stated above and initial sizes of compartmental populations (s(0)=0.9,i(0)=0.7,r(0)=0.5,w(0)=0.3).

Conclusion

We proposed a stochastic model for the novel corona virus disease, because spreading of the covid-19 is not deterministic and having stochastic effect. We formulated the model for covid-19 by varying the transmission co-efficient. Moreover we discussed the existence analysis along with uniqueness for the global solution and showed that the model is well-posed. We then also showed the extinction of the problem as well as persistence and obtained conditions in term of parameters and intensity of white noise. To support the theoretical findings, we used a numerical method of stochastic Euler Maruyama technique and presented numerical simulation. It could be noted from the simulation of the proposed model that there is a great influence of the white noise intensity on the transmission of the novel corona virus disease. The extinction of the covid-19 infected population is directly proportional to the noise intensity, i.e., to increase the value of the noise intensity will exponentially decrease the infection. Beside from this one the persisting of the novel corona virus are proportional inversely to the intensity of white noise i.e., disease persisting decreases if we increase the intensity of white noise.

In a near future a more general model with different sources of randomness where each population group has a different Brownian motion could be investigated.

Declaration of Competing Interest

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Acknowledgment

We would like to express our sincere appreciation to the United Arab Emirates University Research Office for the financial support of UPAR Grant No. 31S369. We also would like to thank the anonymous reviewers for providing constructive comments, which have resulted in enhancing the paper. The usual disclaimer applies however.

Footnotes

1

for more details on simulating SDEs the reader can refer to the books [36], [37].

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