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Main responses induced by oxidative damage and the inflammatory process, and involving peroxisome proliferator-activated receptors, PPARα and PPARγ, during the obesity-related cardiac fibrosis process. CRP: higher C-reactive protein; AKT: protein kinase B; GSK3β: glycogen synthase kinase 3 beta; NADPH: nicotinamide adenine dinucleotide phosphate reduced; ROS: reactive oxygen species.
