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Expression of ion channels in WT and HO-1 KO hiPSC.3-CMs. (A) RNA-seq-GO term: cardiac muscle cell potential involved in contraction. (B) RNA-seq: normalized counts for CACNA1c gene. qRT-PCR analysis of (C) KCNQ1, (D) KCNH2, (E) SCN5a, and (F) CACNA1c. Expression was normalized to TNNT2 levels. Bars represent mean ± SD of N = 3 experiments. Dots, squares and triangles represent each replicate for corresponding groups. * p < 0.05, one-way ANOVA test.
