Table 1.
Details of the tested nutraceutical molecules including their effect on sapje larvae (n = 40 for each treatment).
| Bioactive Compound | Concentration (μM) | Effect | Source |
|---|---|---|---|
| Simvastatin | 50 | Toxic | Sigma |
| 10 | Toxic | ||
| 5 | Toxic | ||
| 1 | Toxic | ||
| Idebenone | 5 | Phenotype retained | Sigma |
| 1 | Phenotype retained | ||
| Pterostilbene | 10 | Toxic | Sigma |
| 5 | Phenotype retained | ||
| 2 | Partial rescue | ||
| 1 | Phenotype retained | ||
| Resveratrol | 1 | Partial rescue | Sigma |
| 0.5 | Phenotype retained | ||
| Curcumin | 13 | Phenotype retained | Natural Products Library |
| 5 | Phenotype retained | ||
| 3 | Phenotype retained | ||
| Genistein | 9 | Phenotype retained | Natural Products Library |
| Daidzein | 9 | Phenotype retained | Natural Products Library |
| Actinomycin D | 2 | Phenotype retained | Natural Products Library |
| Gingerol | 8 | Phenotype retained | Natural Products Library |
| 4 | Partial rescue and increased motility | ||
| Colchicine | 6 | Phenotype retained | Natural Products Library |
| Cyclosporin A | 2 | Toxic | Natural Products Library |
| Camptotechine | 7 | Toxic | Natural Products Library |
| E64D | 7 | Phenotype retained | Natural Products Library |
| 4 | Phenotype retained | ||
| Gossypol | 5 | Phenotype retained | Natural Products Library |
| 2 | Phenotype retained | ||
| Epigallocatechin | 5 | Phenotype retained | Natural Products Library |
| 3 | Phenotype retained | ||
| Quercetin | 7 | Phenotype retained | Natural Products Library |
| Resveratrol | 11 | Phenotype retained | Natural Products Library |
| 5 | Partial rescue | ||
| Shikonin | 8 | Phenotype retained | Natural Products Library |
| 4 | Phenotype retained | ||
| Kaempferol | 8 | Phenotype retained | Natural Products Library |
| 4 | Phenotype retained | ||
| Rottlerin | 5 | Toxic | Natural Products Library |
| 2 | Phenotype retained | ||
| Tomatidine | 6 | Phenotype retained | Natural Products Library |
| 3 | Phenotype retained | ||
| Ferulic Acid | 12 | Toxic | Natural Products Library |
| Flavokawain A | 8 | Toxic | Natural Products Library |
| 4 | Partial rescue |