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A cargo for selective ubiquitin-dependent autophagy, e.g., bacteria, aggregated protein or damaged mitochondria, is labeled by Ub chain. The cargo is recognized by autophagy receptors on the phagosomal membrane and subsequently maturation leading to the emergence of autophagosome occurs. The autolysosome is formed after fusion of autophagosome with lysosome, where the cargo is degraded. LC3—microtubule-associated protein 1 light chain 3, Ub—ubiquitin.
