Figure 5.
Determination of the sliding coefficient of friction (CoF) and mobility time of film-coated tablets with KIR as the control and fixed at 10% w/w. Coulomb’s friction model FF = µFN was used to determine the CoF by using the weight to run its course on a 3D SLA printed in vitro oral apparatus, and it can be seen that the binary and/or ternary addition of λ-carrageenan and/or gelatin in combination effectively reduced the in vitro friction forces exhibited by the control KIR. OEZ yielded the lowest resistance to tangential motion, exhibiting a relatively superior wet-slip profile than any film coating system (ANOVA, p < 0.05).