Table 6. . Significant probes common between diagnosed and presymptomatic dementia groups.

Probe	Probe	Location	Timepoint	Status	Mean (%)	Δ Case versus controls	p-value
APP	cg08542030	chr21:27306498	Baseline	Control	76.66%	1.41%	0.02
				Presymptomatic	78.07%
			Follow-up	Control	75.36%	2.39%	0.01
				Dementia	77.75%
	cg17728373	chr21:27404776	Baseline	Control	58.34%	2.16%	0.03
				Presymptomatic	60.51%
			Follow-up	Control	57.07%	3.86%	0.01
				Dementia	60.92%
	cg22552084	chr21:27497496	Baseline	Control	61.80%	1.90%	0.03
				Presymptomatic	63.69%
			Follow-up	Control	61.16%	2.68%	0.03
				Dementia	63.84%
	cg03015479	chr21:27544797	Baseline	Control	68.09%	1.82%	0.04
				Presymptomatic	69.91%
			Follow-up	Control	66.64%	3.32%	0.007
				Dementia	69.96%
BDNF	cg26949694	chr11:27742060	Baseline	Control	17.86%	-1.05%	0.03
				Presymptomatic	16.82%
			Follow-up	Control	19.00%	-2.30%	0.03
				Dementia	16.69%
	cg01225698	chr11:27742355	Baseline	Control	11.70%	-1.05%	0.02
				Presymptomatic	10.66%
			Follow-up	Control	12.29%	-1.83%	0.02
				Dementia	10.47%
	cg27351358	chr11:27743258	Baseline	Control	8.13%	-0.92%	0.02
				Presymptomatic	7.21%
			Follow-up	Control	8.33%	-1.39%	0.01
				Dementia	6.94%
SNCA	cg06176111	chr4:90674837	Baseline	Control	62.15%	1.57%	0.05
				Presymptomatic	63.72%
			Follow-up	Control	61.87%	2.48%	0.04
				Dementia	64.34%
	cg17045024	chr4:90758207	Baseline	Control	18.89%	-1.89%	0.04
				Presymptomatic	17.00%
			Follow-up	Control	19.72%	-3.36%	0.03
				Dementia	16.36%
	cg00119181	chr4:90758537	Baseline	Control	8.40%	-1.20%	0.05
				Presymptomatic	7.21%
			Follow-up	Control	9.53%	-2.34%	0.02
				Dementia	7.20%