Table 1.
Commercially available hybrid closed-loop systems
| Component | Medtronic 670G | Medtronic 780G | CamAPS FX | Control-IQ |
|---|---|---|---|---|
| Algorithm | PID with insulin feedback | PID with insulin feedback | Treat to target adaptive MPC (Cambridge algorithm) | Treat to range predictive algorithm |
| Insulin pump | 670G | 780G | Dana RS, Dana-i | Tandem t:slim X2 |
| CGM system | Guardian 3 (requires ~4–6 fingersticks/day) | Guardian 3 (requires ~4 fingersticks/day) |
Dexcom G6 (factory calibrated, optional calibration) |
Dexcom G6 (factory calibrated, optional calibration) |
| Target glucose | Fixed target: 6.7 mmol/l | Target: 5.6 mmol/l (default) or 6.7 mmol/l | Target: 5.8 mmol/l (default); customisable between 4.4 mmol/l and 11 mmol/l | Fixed target range: 6.2–8.9 mmol/l |
| Optional activity target | Optional activity target | Night mode: 6.2–6.7 mmol/l | ||
| Optional activity target | Optional activity target | |||
| Algorithm learning | Based on TDD | Based on TDD | Adapts to prandial and diurnal patterns | None |
| Compatible downloading software | Carelink; manual downloading of pump required | Carelink; automated app compatibility | Diasend; automated download | Clarity: sensor data |
| Diasend/Glooko; manual downloading of pump required |
TDD, total daily dose