Symptom severity among patients in the pre‐evidence and post‐evidence groups. Bars represent mean symptom severity scores. The number of patients for whom individual Edmonton Symptom Assessment System symptoms were available ranged from 227 to 232 pre‐evidence and from 395 to 402 post‐evidence. The Holm‐Bonferroni method was used to correct for multiple testing, with the following levels of significance: pain (p = .83), tiredness (p = .001), nausea (p = .4), depression (p = .4), anxiety (p = .4), drowsiness (p = .24), appetite (p = .08), wellbeing (p = .21), and shortness of breath (p = .4).