Abstract
Hypertension represents a major burden in Asia, with a high prevalence rate but poor level of awareness and control reported in many countries in the region. Home blood pressure monitoring has been validated as an accurate and reliable measure of blood pressure that can help guide hypertension treatment as well as identify masked and white‐coat hypertension. Despite its benefits, there has been limited research into home blood pressure monitoring in Asia. The authors reviewed the current evidence on home blood pressure monitoring in Asia, including but not limited to published literature, data presented at congresses, and national hypertension management guidelines to determine the current utilization of home blood pressure monitoring in clinical practice in the region. Public policies to enable greater access to home blood pressure monitoring and its use in clinical care would add considerably to improving hypertension outcomes in Asia.
Keywords: Asia, blood pressure control, home blood pressure monitoring, hypertension
1. BURDEN OF HYPERTENSION IN ASIA
Hypertension is the leading preventable cause of premature death worldwide.1, 2 Globally, an estimated 1.4 billion persons in 2010 had hypertension, with the majority residing in low‐ and middle‐income countries. Disparities in hypertension prevalence, awareness, treatment, and control rates are particularly evident in Asia, a diverse region that has seen significant increases in hypertension prevalence during the past 30 years.3 A systematic review of data from 33 Asian countries reported an overall hypertension prevalence of 27% (range, 13.6%–47.9%).4 Despite age‐standardized hypertension prevalence rates having recently shown a slight downward trend in almost all Asian countries,5 there is still enormous variability in the rates of awareness, treatment, and control of hypertension in the region (Table 1).
Table 1.
Prevalence, % | Awareness, % | Treated, % | Controlled, % | Reference | |
---|---|---|---|---|---|
China | 25.2 | 46.5 | 41.1 | 13.8 | 16 |
Hong Kong | 31.6 | 46.2 | 69.7 | 25.8 | 22 |
India | 29.8 |
25.1 (rural) 41.9 (urban) |
24.9 (rural) 37.6 (urban) |
10.7 (rural) 20.2 (urban) |
26 |
Indonesia | 26.5 | 35.8 | NR | NR | 29 |
Japan |
60.0 (men) 45.0 (women) |
NR |
52.8 (men) 52.8 (women) |
31.7 (men) 42.0 (women) |
33 |
Korea |
32.9 (men) 23.7 (women) |
58.5 (men) 76.1 (women) |
51.7 (men) 71.3 (women) |
36.9 (men) 49.4 (women) |
37 |
Malaysia | 30.3 | 43.2 | 81.2 | 26.3 | 44, 60 |
Pakistan | 50.3 | 29.6 | 18.0 | 5.5 | 49 |
Philippines | 28.0 | 67.8 | 75.0 | 27.0 | 51 |
Singapore | 23.5 | 73.7 | NR | 69.1 | 53 |
Taiwan | 20.8 | 72.1 | 89.4 | 70.2 | NHANES, 2013–2016, unpublished data |
Thailand | 24.7 | 55.3 | 49.2 | 60.4 | NHES, 2014–2015, unpublished data |
Abbreviations: NHANES, National Health and Nutrition Examination Survey; NHES, National Health Examination Survey; NR, not reported.
Several factors contribute to the current hypertension burden in Asia, including acculturation to Western lifestyle, modernization, and urbanization.3 Other characteristics of hypertension in Asia that may contribute to the overall burden of disease include high salt intake with high salt sensitivity and an epidemic of obesity with concomitant metabolic syndrome.6
There is growing acknowledgment for the role of home blood pressure monitoring (HBPM) to evaluate and guide management of hypertension.7 HBPM is a simple tool for measuring blood pressure (BP) at home and is recommended by guidelines to obtain reliable BP recordings because of its potential to improve hypertension control.8 Home systolic BP (SBP) <135 mm Hg and diastolic BP (DBP) <85 mm Hg are typically considered normal.9 In patients with hypertension and other risk factors, a more strict SBP level of <130 mm Hg can be recommended.10 In this article, the HOPE Asia (Hypertension Cardiovascular Outcome Prevention and Evidence in Asia) Network review the current evidence on HBPM in Asia, including but not limited to the key published literature from the region, data presented at congresses, and national hypertension management guidelines to determine the current utilization of HBPM in clinical practice in Asia.
2. VALUE OF HBPM IN THE MANAGEMENT OF HYPERTENSION
Home BP monitoring (HBPM) has been heralded as a useful and reliable measure of BP. Rather than replacing clinic BP measurements and ambulatory BP monitoring (ABPM), HBPM is a complementary tool that helps to eliminate the white‐coat effect and identify masked hypertension.8 HBPM can also improve patient awareness and treatment adherence by giving all patients with hypertension and their family members a more active role in the management of the disease.
The evidence supporting the use of out‐of‐clinic monitoring in general and HBPM in particular has increased substantially in recent years and a systematic review found that clinic BP measurements yield higher BP levels than HBPM.11 In the case of SBP, differences between clinic BP and HBPM increase with age and tend to be greater in men than women and in patients not receiving antihypertensive treatment.11 HBPM can diagnose normotension with more certainty and the measurements correlate better with target organ damage and cardiovascular outcomes than clinic BP.11, 12, 13 HBPM shows diagnostic agreement with ABPM in this regard and has also demonstrated superiority to clinic BP in terms of diagnosing uncontrolled hypertension, assessing antihypertensive drug effects, and improving patient adherence and hypertension control.11, 12, 13 It is also more likely to yield reductions in antihypertensive medications and less likely to be associated with therapeutic inertia.14
3. CURRENT STATUS OF HBPM IN ASIA
Recent findings from the Edvantage 360° multinational mixed‐methods observational study suggest that despite a good understanding of the causes and consequences of hypertension among persons with high BP in Asia, there is a lack of urgency to control BP.15 Furthermore, doctors and patients have different expectations of one another, with a different view of what constitutes successful hypertension management and who is most responsible for achieving this goal. These findings suggest that doctors may provide better care for their patients by ensuring a common understanding of successful disease management. Moreover, the inclusion of HBPM in a person's care may be a useful strategy to ensure patients play a more active role in disease management.
The following country/region scenarios aim to illustrate the current status of HBPM utilization throughout Asia. The evidence was gathered and discussed during a meeting of the authors, who represent key figures among the national hypertension societies in Asia. Where published evidence was limited, the authors provided their own expert opinion on the current status in their country.
3.1. China
3.1.1. Hypertension prevalence
Figures published by the National Health and Family Planning Commission in 2015 revealed that the prevalence of hypertension in China is 25.2%, with 46.5%, 41.1%, and 13.8% of patients with hypertension aware of their condition, treated, and controlled, respectively.16
3.1.2. Current status of HBPM in hypertension management
A number of studies involving HBPM have been conducted in China, including the ongoing ABPR (China Ambulatory and Home Blood Pressure Registry) in patients with hypertension. One study involving 3547 patients from the China ABPR utilized both 24‐hour ABPM and 7‐day HBPM to investigate the size of the morning BP surge in Chinese patients.17 Approximately half of the patients had morning hypertension based on HBPM readings. An additional analysis of 1774 patients from the China ABPR found that HBPM had high specificity but low sensitivity in the diagnosis of white‐coat and masked hypertension, and may therefore serve as a complementary tool to ABPM.18 One cross‐sectional survey conducted in 1915 patients with hypertension in Shanghai found that 1011 (52.8%) individuals used HBPM.19 However, only 46.5% of HBPM users performed it using arm‐cuff electronic devices, and the authors concluded that patient education is needed to improve the accuracy of HBPM in China.
3.1.3. Hypertension and HBPM guidelines
Physicians in China currently follow the 2010 Chinese guidelines for the management of hypertension,20 as well as the China consensus on the use of HBPM in the management of hypertension whose recommendations are summarized in Table 2.21
Table 2.
Recommendations |
---|
Home BP should be measured with validated automated upper‐arm cuff devices that operate through the oscillometric technique |
Home BP should be measured twice with an interval of 1 min, and the mean value used as the BP value for that occasion |
The morning measurement should be taken within a few hours of waking up, after urination, before drug intake, and before breakfast, after 5 min of rest in a sitting position; the evening measurement should be taken before going to bed, after a meal, after drug intake, and after shower or bath (if any), after 5 min of rest in a sitting position. The legs should not be crossed when sitting |
For the diagnosis and treatment of hypertension based on home BP, the mean of the values measured for 5 to 7 consecutive days should be used |
Home BP ≥135/85 mm Hg indicates hypertension, and <130/80 mm Hg indicates normotension. The presence of home BP in the range 130–134/80–84 mm Hg requires ambulatory BP monitoring |
Antihypertensive treatment strategies should target a home BP level of <135/85 mm Hg |
Abbreviation: BP, blood pressure.
3.2. Hong Kong
3.2.1. Hypertension prevalence
A family cohort study from 2009–2011 reported a hypertension prevalence rate of 31.6% among adults aged 20 years and older in Hong Kong.22
3.2.2. Current status of HBPM in hypertension management
There has been limited investigation into the role of HBPM in Hong Kong, but two studies have been reported in recent years. The first was a cluster randomized controlled trial in which half of 240 patients with hypertension received an education intervention focused on HBPM device use, with the other half receiving usual care.23 A nonsignificant SBP drop of 1.88 mm Hg and a significant DBP drop of 3.84 mm Hg were observed in the intervention group at 3 months, indicating that a structured HBPM education program has the potential to improve BP control at least over the short term. The second study, a cross‐sectional survey, found that 59% of patients with hypertension from a regional primary care clinic performed HBPM, with no significant difference in BP levels between users and nonusers of HBPM.24
3.2.3. Hypertension and HBPM guidelines
The Food and Health Bureau released their latest framework for hypertension management in primary care in 2013.25 This briefly highlighted the advantages of HBPM in providing information on response to treatment and improving adherence, but raises the potential issue of unsupervised alteration of medication.
3.3. India
3.3.1. Hypertension prevalence
A 2014 meta‐analysis found that the prevalence rate of hypertension in India was 29.8%, with the prevalence in the urban population significantly higher than the rural population.26
3.3.2. Current status of HBPM in hypertension management
There are limited data for India on home BP and HBPM. Although HBPM is referenced in local guidelines,27 lack of awareness and poor compliance among patients contribute to a lack of uptake and impact, respectively. A single observational study of 30 treatment‐naive patients found that nocturnal BP measurement using an HBPM device may be a reliable and cost‐effective method for detecting the early signs of end organ damage, such as left ventricular hypertrophy.28
3.3.3. Hypertension and HBPM guidelines
The Association of Physicians of India published their latest guidelines on hypertension management in 2013.27 As part of maintenance and follow‐up therapy, they recommend BP to be measured at least once every 2 weeks either at home or in the clinic.
3.4. Indonesia
3.4.1. Hypertension prevalence
Data from the 2013 Basic Health Research Survey showed a hypertension prevalence rate of 26.5% among adults aged 18 years and older.29
3.4.2. Current status of HBPM in hypertension management
Among patients with hypertension, HBPM is not routinely performed in Indonesia, with lack of awareness, device availability, and the perception that digital instruments lack accuracy for the measurement of BP seen as the main barriers to uptake. Data presented at congresses showed that SBP and DBP assessed using HBPM were significantly correlated with left ventricular mass index.30 Another study found that HBPM is a reliable measure of BP variability, with a tendency towards a positive correlation to arterial stiffness.31
3.4.3. Hypertension and HBPM guidelines
Several guidelines are in place in Indonesia to optimize BP control, including those issued by the Indonesian Society of Hypertension (INASH) and the Indonesian Heart Association, both in 2015. The INASH guidelines in particular were adopted based on the European Society of Hypertension (ESH)/European Society of Cardiology (ESC) 2013 guidelines.32
3.5. Japan
3.5.1. Hypertension prevalence
Hypertension prevalence increases steeply with age in Japan and a national survey in 2010 found that 60% of Japanese men and 45% of women older than 30 years have hypertension, equivalent to around 43 million people.33
3.5.2. Current status of HBPM in hypertension management
Although treatment and control rates have increased in recent years, only around 30% of men and 40% of women have controlled BP. In Japan, HBPM is popular in clinical practice, and, where barriers do exist to its uptake and impact, these likely reflect patients’ abilities to manage home BP data and take steps accordingly.
A multitude of studies have evaluated the use of HBPM in Japan. Among these, the Ohasama study evaluated HBPM in 1702 people aged 40 years and older in the general population and found a linear relationship between home BP levels and the risk of hemorrhagic and ischemic stroke.34 The J‐HOP (Japan Morning Surge‐Home Blood Pressure) study was intended to determine the optimal time schedule for HBPM to best predict stroke and coronary artery disease (CAD) in 4310 Japanese people with a history of or risk factors for cardiovascular disease.35 During a mean follow‐up of 4 years, morning SBP measured at home was shown to improve the discrimination of incident stroke beyond traditional risk factors that included clinic SBP, whereas the addition of evening SBP reduced the discrimination of incident stroke. Although neither morning nor evening SBP improved risk prediction of CAD in the J‐HOP study, a larger study of more than 21 000 patients with treated hypertension did find a strong correlation between morning home BP and future CAD and stroke events.36 Moreover, the data suggested that morning home BP might be superior to clinic BP in this regard.
3.5.3. Hypertension and HBPM guidelines
Physicians in Japan follow the Japanese Society of Hypertension (JSH) 2014 guidelines to support optimal BP control in their patients.33 These include formal recommendations for HBPM, which are summarized in Table 3.
Table 3.
Recommendations |
---|
Home BP should be measured with upper‐arm cuff devices using the cuff‐oscillometric method |
Home BP should be measured twice and the mean value used as the BP value on that occasion |
The morning measurement should be taken within 1 h of waking, after urination, before dosing in the morning, and before breakfast, after 1 to 2 min of rest in a sitting position; the evening measurement should be taken prior to retiring to bed, after 1 to 2 min of rest in a sitting position. The legs should not be crossed when sitting |
To evaluate hypertension, normal BP, and the effects of antihypertensive drugs based on home BP, the mean of the values measured 5 to 7 d/wk should be used |
Home BP of 135/85 mm Hg indicates hypertension |
When there is a discrepancy of diagnosis between clinic and home BP, a home BP‐based diagnosis should have priority |
Antihypertensive treatment strategies should target a home BP level of <135/85 mm Hg for young, middle‐aged, and early‐phase elderly patients, <145/85 mm Hg for late‐phase elderly patients (<135/85 mm Hg if tolerated), <125/75 mm Hg in patients with diabetes mellitus or chronic kidney disease, and <135/85 mm Hg in patients with cerebrovascular diseases |
Abbreviation: BP, blood pressure.
3.6. Korea
3.6.1. Hypertension prevalence
The prevalence of hypertension in Korea in 2011 was 28.5% among adults older than 30 years, with a sharp increase in prevalence among older adults.37 Overall, less than half of the Korean population has normal BP.
3.6.2. Current status of HBPM in hypertension management
HBPM is routinely used in Korea, but the results of a recent survey suggest barriers to use do exist. In particular, there is a lack of resources to both initiate and maintain HBPM. A total of 55% of physicians reported difficulties in recommending HBPM and only 6.6% fully explained the HBPM protocol to their patients during visits. Other barriers include a lack of trust in the accuracy of HBPM devices and the ability of patients to perform HBPM accurately, as well as a general low public awareness of HBPM.38 Nonvalidated HBPM devices are routinely used in clinical practice, reinforcing this perception.39
Considerable effort has been made to study HBPM in Korea. Local data have shown that HBPM is equivalent to ABPM and superior to clinic BP in predicting subclinical target organ damage in patients with untreated hypertension.40 In a randomized controlled trial of patients with hypertension, usual clinic care plus HBPM was used as a control group to evaluate the effectiveness of remote patient monitoring with or without remote physician care in reducing clinic BP.41 All three interventions resulted in similar SBP at 24 weeks. Furthermore, HBPM was shown to be a useful tool for discriminating white‐coat hypertension and masked hypertension in Korean patients with diagnosed hypertension who had not changed their oral antihypertensive medication in the past 6 months.42 In those with masked hypertension, mean clinic BP was 130/80 mm Hg compared with 137/86 mm Hg for home BP. Conversely, among patients with white‐coat hypertension, the mean clinic BP was 149/86 mm Hg compared with a home BP of 124/75 mm Hg. A further study investigated the optimal duration of HBPM for the diagnosis of hypertension and found that a 3‐, 5‐, or 7‐day protocol all had similar diagnostic accuracy when compared with ABPM.43
3.6.3. Hypertension and HBPM guidelines
Physicians refer to the 2013 Korean Society of Hypertension (KSH) guidelines,37 as well as international hypertension guidelines when managing patients. The 2013 KSH guidelines include specific recommendations on HBPM and are summarized in Table 4.
Table 4.
Requirement | Description |
---|---|
Upper arm cuff | Wrist device should only be used when extreme obesity can cause errors; the device should be kept at the level of the heart |
Time of measurement |
|
Frequency of measurement | One to three times per occasion |
Period of measurement | As long as possible; 1 wk or more for the diagnosis of hypertension; over at least 5 to 7 d immediately preceding the visit during follow‐up of treatment |
Adapted from Shin et al.37 .
3.7. Malaysia
3.7.1. Hypertension prevalence
According to 2015 National Health and Morbidity Survey data, the prevalence of hypertension was 30.3% in adults 18 years and older.44
3.7.2. Current status of HBPM in hypertension management
HBPM is more commonly used in urban areas, where the prevalence of hypertension is highest, but is not routinely used in clinical practice. The major barriers to uptake of HBPM are a lack of awareness among physicians, the cost of devices, and a lack of patient education. A nationwide telephone survey of more than 2500 participants with hypertension found that although 94% of respondents were aware of the importance of controlling hypertension, around 20% were not currently taking antihypertensive medication, and the authors advocated for strategies that motivated patient adherence, including HBPM.45 A qualitative study explored the influence of self‐owned HBPM devices in primary care patients with hypertension and found that patients who self‐initiated HBPM reported a higher level of self‐efficacy in the management of hypertension.46 Furthermore, a small study at a primary care clinic in Kuala Lumpur assessed patient acceptance of a home BP telemonitoring service and found that patients needed help to interpret the meaning of monitored BP readings, suggesting that the implementation of HBPM requires a degree of patient education to optimize uptake.47
3.7.3. Hypertension and HBPM guidelines
Currently, physicians follow the Malaysian 2013 hypertension guidelines,48 as well as relevant guidelines from Europe and America.32 While the Malaysian guidelines do discuss the merits of HBPM and how it should be performed, they do not explicitly recommend its use in the management of hypertension.
3.8. Pakistan
3.8.1. Hypertension prevalence
The prevalence rate of hypertension in those aged 18 to 69 years was estimated to be around 50% in a population‐based survey from November 2013 to April 2014, with 70.4% of patients with hypertension being unaware of its presence.49
3.8.2. Current status of HBPM in hypertension management
No studies are currently available on HBPM usage in Pakistan but a study is being conducted to compare HBPM with ABPM in 130 patients with known hypertension. Although HBPM is being used in Pakistan, its use is not routine, with cost as a major barrier to uptake. Other barriers include a lack of awareness of its utility among patients and physicians, low education and literacy levels in the general population, variability of results obtained using HBPM as a result of a large number of nonvalidated monitors on the market, and a lack of awareness of correct methodology in the use of HBPM with a resultant lack of confidence in HBPM among physicians.
3.8.3. Hypertension and HBPM guidelines
National guidelines published in 2009 by the Pakistan Hypertension League and Pakistan Cardiac Society are available to support the management of hypertension in Pakistan,50 but many physicians also refer to more recent National Institute for Health and Care Excellence and ESH/ESC guidelines.
3.9. Philippines
3.9.1. Hypertension prevalence
Data from the nationwide PRESYON 3 survey indicated a hypertension prevalence rate of 28%, with 75% of patients receiving treatment and 27% of those achieving adequate BP control.51
3.9.2. Current status of HBPM in hypertension management
HBPM is performed in the Philippines, but not routinely, and there are no published data on the use of HBPM in the country. HBPM is currently used to investigate the status of BP control in patients with known hypertension who are taking treatment but with uncontrolled BP on follow‐up. Some specialists use HBPM to make a diagnosis of hypertension in conjunction with clinic BP. Barriers to the use of HBPM include the cost and availability of HBPM devices, with only around 25% of the population with hypertension currently having access to such devices. Another barrier is the lack of trust among patients regarding the accuracy of their digital BP devices.
3.9.3. Hypertension and HBPM guidelines
The Philippine Society of Hypertension released guidelines in 2011,52 but international guidelines continue to be widely used. There is a tendency among physicians to use US guidelines more than any other, with greater recognition of the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) guidelines despite the recent publication of the Eighth Joint National Committee (JNC 8) guidelines.
3.10. Singapore
3.10.1. Hypertension prevalence
Ministry of Health data last published in 2010 showed that the prevalence rate of hypertension is 23.5% in adults aged 30 to 69 years.53 Among those with hypertension, 26.3% had not been previously diagnosed. Encouragingly, 69.1% of patients with treated hypertension had good BP control.
3.10.2. Current status of HBPM in hypertension management
A randomized cross‐sectional survey was implemented to investigate the use of HBPM in a local, multiracial population of patients with hypertension. The factors associated with HBPM use were higher patient socioeconomic status and documented DBP.54 Non‐use of HBPM was associated with a failure to recognize the benefits of HBPM, lack of awareness of HBPM, lack of understanding of device operation, and perception of device inaccuracy. Overall, more than 60% of survey participants were aware of HBPM but only 24% of patients used it. In recent years, HBPM has been more routinely adopted in Singapore, with physicians willing to recommend its use to their patients, and patients increasingly electing to use HBPM. Potential barriers to further uptake of HBPM include reluctance among patients to perform HBPM and device costs.
3.10.3. Hypertension and HBPM guidelines
Most physicians in Singapore follow international guidelines such as the ESH/ESC and JNC guidelines for BP control. The latest national guidelines were published by the Ministry of Health in 2005,55 and new guidelines are pending release. HBPM is recommended in patients suspected of having white‐coat or masked hypertension but not as a routine measurement for the diagnosis and control of hypertension.
3.11. Taiwan
3.11.1. Hypertension prevalence
The 2013–2016 National Health and Nutrition Examination Survey found that the hypertension prevalence (adjusted according to the World Health Organization standardized population) was 20.8% in adults 19 years and older (unpublished data).
3.11.2. Current status of HBPM in hypertension management
HBPM is often performed in Taiwan, but there has been no formal survey on the availability of home BP monitors in households. Most cardiologists generally encourage their patients to measure BP at home. Some physicians may have the perception that HBPM is not a reliable measure of BP. A study comparing clinic BP and HBPM with ABPM in patients undergoing peritoneal dialysis concluded that clinic and home BP measurements were correlated with ABPM.56 A hypertension registry involving more than 2000 people with treated hypertension is ongoing, with data on HBPM expected to be analyzed in the near future.
3.11.3. Hypertension and HBPM guidelines
Physicians in Taiwan typically follow guidelines of the Taiwan Society of Cardiology and the Taiwan Hypertension Society.57 HBPM is included within their diagnosis algorithm as a complementary tool to office BP to help confirm white‐coat or masked hypertension.
3.12. Thailand
3.12.1. Hypertension prevalence
According to the unpublished findings of the fifth National Health Examination Survey (2014–2015), the prevalence rate of hypertension was 24.7%, with an awareness rate of 55.3%.
3.12.2. Current status of HBPM in hypertension management
HBPM is used in Thailand mainly to detect white‐coat and masked hypertension, and for self‐BP monitoring where affordable. HBPM has also been used by health workers to monitor BP among villagers in remote rural areas. The main barriers to its use are ignorance of its value among physicians, availability, and cost of the device. A number of studies have evaluated HBPM in Thailand. Among these, one study used HBPM to determine the clinical characteristics of patients with hypertension whose BP could be normalized for at least 1 year on treatment and remain normal following drug withdrawal.58 The only factor that was predictive of sustained normotensive outcome was male sex.
3.12.3. Hypertension and HBPM guidelines
Physicians in Thailand refer to the local Thai Hypertension Society 2015 guidelines for optimizing the management of hypertension, which briefly highlight the advantage of HBPM in detecting white‐coat and masked hypertension.59 The ESH/ESC guidelines are also commonly used.
4. CONCLUSIONS AND FUTURE PERSPECTIVES
Despite hypertension being the most common modifiable risk factor for cardiovascular disease,14 hypertension control remains a serious challenge throughout Asia. Clearly there is an imperative for finding local solutions to improve hypertension management and this is reinforced by the Edvantage 360° study, which points to a need for physicians to better align with their patients for a common understanding of successful hypertension management.15 One way to achieve this is through the use of HBPM, which has the potential to increase a person's involvement in the management of their own disease. Since its introduction, HBPM has gained in popularity for the diagnosis, monitoring, and treatment of hypertension because of its lack of white‐coat effect, its ability to provide information of prognostic value, the close relationship of derived BP values with cardiovascular risk, and its association with larger BP declines when used for treatment monitoring and adjustment. Despite this evidence, its adoption in Asia has been slow. Considerable research into HBPM has been conducted in Japan and Korea, but elsewhere in the region the data are lacking and this may be the result of vast differences in healthcare provision and research funding available across Asia, inhibiting research into HBPM. Even where local data are available, HBPM utilization may be limited because of cost constraints, lack of understanding on how to use the devices by patients, and the absence of formal recommendations on HBPM in national guidelines. As such, there is a need to drive further research on HBPM specifically in Asia to generate the local evidence base to support its uptake. As devices become more affordable and additional data are generated, a concerted effort should be made among healthcare professionals in Asia to promote the value of HBPM in improving hypertension control in patients and to incorporate its use into national hypertension management guidelines.
DISCLOSURES
CH Chen has received honoraria as a member of a speaker's bureau for Pfizer. YC Chia has received honoraria and sponsorship to attend conferences and CME seminars from Abbott, Bayer, GlaxoSmithKline, Menarini, Merck Sharp & Dohme, Novartis, Orient Europharma, Pfizer, and Sanofi; and a research grant from Pfizer. R Divinagracia has received honoraria as a member of speakers’ bureaus for Bayer, Novartis, and Pfizer. K Kario has received research grants from A&D Co., Bayer Yakuhin, Boehringer Ingelheim, Daiichi Sankyo, EA Pharma, Fukuda Denshi, Medtronic, Mitsubishi Tanabe Pharma Corporation, Mochida Pharmaceutical Co., Omron Healthcare, Otsuka, Takeda, and Teijin Pharma Co.; and honoraria from Daiichi Sankyo, Omron Healthcare, and Takeda. S Park has received research grants and honoraria from Pfizer. S Siddique has received honoraria from Bayer, GlaxoSmithKline, Pfizer, and Servier; and travel, accommodation and conference registration support from Atco Pharmaceutical, Highnoon Laboratories, Horizon Pharma, and Pfizer. GP Sogunuru has received a research grant related to hypertension monitoring and treatment from Pfizer. JG Wang has received research grants from Bayer, Pfizer, and Phillips; and lecture and consulting fees from Bayer, Daiichi Sankyo, MSD, Pfizer, Sanofi, and Servier. L Wong has received honoraria from Bristol‐Myers Squibb and Pfizer. Y Zhang has received research grants from Bayer, Novartis, and Shuanghe; and lecture fees from Bayer, Daiichi Sankyo, Novartis, Pfizer, Sanofi, Servier, and Takeda. All other authors report no potential conflicts of interest in relation to this article.
ACKNOWLEDGMENTS
Editorial and writing support was provided by Howard Christian and Chris Facey of MIMS (Hong Kong) Limited and was funded by Pfizer.
Chia YC, Buranakitjaroen P, Chen CH, et al. Current status of home blood pressure monitoring in Asia: Statement from the HOPE Asia Network. J Clin Hypertens. 2017;19:1192–1201. 10.1111/jch.13058
This statement on blood pressure measurement is supported by the World Hypertension League.
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