Table F1.

Ninety-five percent confidence intervals for numbers of causal SNPs

Phenotype	nb	nc	nd	ncausal
SCZ 2014	[5.29e5, 5.83e5]	[1.73e4, 2.86e4]	[2.81e3, 3.11e3]	[5.54e5, 6.10e5]
BIP	[3.99e5, 8.52e5]	[1.66e4, 3.55e4]	—–	[4.25e5, 8.78e5]
CD	[8.57e3, 9.44e3]	[1.43e3, 1.61e3]	[1, 2]	[1.01e4, 1.10e4]
UC	[1.02e4, 1.25e4]	[1.27e3, 1.60e3]	[1, 2]	[1.16e4, 1.39e4]
CAD	[1.81e4, 2.12e4]	[814, 1.20e3]	[4, 5]	[1.91e4, 2.23e4]
AD Chr19	[50, 110]	[17, 50]	—–	[67, 159]
AD NoC19	[7.75e3, 1.41e4]	[1.72, 417]	—–	[7.92e3, 1.46e4]
ALS Chr9	[3.98e3, 6.58e3]	[4, 10]	—–	[3.98e3, 6.59e3]
Edu	[1.02e5, 1.23e5]	[3.57e4, 5.29e4]	[888, 1.02e3]	[1.39e5, 1.77e5]
IQ 2018	[9.19e4, 9.92e4]	[3.23e4, 3.61e4]	[1.03e4, 1.12e4]	[1.34e5, 1.46e5]
Height 2010	[8.90e3, 9.91e3]	[1.66e3, 2.07e3]	—–	[1.07e4, 1.18e4]
Height 2014	[1.02e4, 1.09e4]	[1.85e3, 2.21e3]	—–	[1.22e4, 1.30e4]
Height 2018	[1.89e4, 2.08e4]	[7.20e3, 8.09e3]	—–	[2.65e4, 2.86e4]
HDL	[2.58e4, 2.95e4]	[178, 350]	[13, 16]	[2.61e4, 2.98e4]
LDL	[5.56e4, 7.21e4]	[388, 539]	[12, 16]	[5.61e4, 7.26e4]
BMI GIANT 2015	[1.67e4, 1.70e4]	[67, 69]	—–	[1.68e4, 1.71e4]
BMI GIANT-UKB 2018	[2.54e4, 2.59e4]	[87, 90]	—–	[2.55e4, 2.60e4]
TC	[1.07e4, 1.34e4]	[132, 227]	[383, 485]	[1.13e4, 1.41e4]

n _causal is the total number of causal SNPs (from the 11 million in the reference panel); n_b, n_c, and n_d are the numbers associated with the “b,” “c,” and “d” Gaussians, respectively. See Table 2. These confidence intervals are likely underestimates (too narrow), due to linkage disequilibrium and a consequent over-counting of the number of degrees of freedom (independent z-scores).