Table 3.
Heritabilities: h2 is the total additive SNP heritability, re-expressed on the liability scale as for the qualitative traits (upper section)
Phenotype | h 2 | %c | ||||
---|---|---|---|---|---|---|
SCZ 2014 | 0.16 | 0.31 | 0.09 | 0.56 | 0.31 | 55.1 |
BIP | 0.16 | 0.37 | —– | 0.53 | 0.26 | 69.7 |
CD | 0.10 | 0.40 | 0.02 | 0.52 | 0.24 | 77.5 |
UC | 0.09 | 0.29 | 0.02 | 0.41 | 0.18 | 72.3 |
CAD | 0.05 | 0.04 | 0.00 | 0.09 | 0.07 | 41.3 |
AD Chr19 | 0.00 | 0.08 | —– | 0.08 | 0.11 | 97.4 |
AD NoC19 | 0.04 | 0.03 | —– | 0.07 | 0.10 | 42.1 |
ALS Chr9 | 0.01 | 0.00 | —– | 0.01 | 0.00 | 37.1 |
Edu | 0.04 | 0.11 | 0.02 | 0.18 | —– | 64.9 |
IQ 2018 | 0.02 | 0.08 | 0.08 | 0.18 | —– | 44.4 |
Height 2010 | 0.08 | 0.13 | —– | 0.22 | —– | 61.0 |
Height 2014 | 0.09 | 0.12 | —– | 0.21 | —– | 58.4 |
Height 2018 | 0.04 | 0.24 | —– | 0.28 | — | 86.0 |
HDL | 0.06 | 0.08 | 0.05 | 0.19 | —– | 40.1 |
LDL | 0.05 | 0.05 | 0.02 | 0.11 | —– | 40.6 |
BMI 2015 | 0.08 | 0.01 | —– | 0.08 | —– | 7.6 |
BMI 2018 | 0.00 | 0.00 | —– | 0.09 | —– | 5.2 |
TC | 0.04 | 0.10 | 0.03 | 0.18 | —– | 59.0 |
, and are the heritabilities associated with the “b,” “c,” and “d” Gaussians, respectively. The last column, labeled %c, gives the percentage of SNP heritability that comes from the “c” Gaussian. Ninety-five percent confidence intervals are in Appendix Table F2. A comparison of the total heritabilities with estimates from our basic model alone (Holland et al. 2020), and with estimates from other models (Zeng et al. 2018; Zhang et al. 2018; Schoech et al. 2019) are given in Appendix Table B1.