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American Journal of Respiratory and Critical Care Medicine logoLink to American Journal of Respiratory and Critical Care Medicine
. 2021 Apr 15;203(8):1045. doi: 10.1164/rccm.v203retraction1

Retraction: Isoniazid and Rifapentine Treatment Eradicates Persistent Mycobacterium tuberculosis in Macaques

PMCID: PMC8048750  PMID: 33856282

The authors of the article (1), published in the February 15, 2020, issue of the Journal, have discovered that infection and 3HP treatment of a cohort of the animals did not conform to the stated experimental protocol. Since analysis of the other cohort of animals that did not experience protocol deviation generated similar results, the conclusions of the article may be correct. However, the authors believe that retraction is appropriate because of the differences in performance of the study, and because the published article does not accurately reflect how all of the animals were infected and treated with 3HP.

Reference

  • 1.Foreman TW, Bucşan AN, Mehra S, Peloquin C, Doyle LA, Russell-Lodrigue K, Gandhi NR, Altman J, Day CL, Ernst JD, Blumberg HM, Rengarajan J, Kaushal D. Isoniazid and rifapentine treatment eradicates persistent Mycobacterium tuberculosis in macaques. Am J Respir Crit Care Med. 2020;201:469–477. doi: 10.1164/rccm.201903-0646OC. [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]

Articles from American Journal of Respiratory and Critical Care Medicine are provided here courtesy of American Thoracic Society

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