The authors of the article (1), published in the February 15, 2020, issue of the Journal, have discovered that infection and 3HP treatment of a cohort of the animals did not conform to the stated experimental protocol. Since analysis of the other cohort of animals that did not experience protocol deviation generated similar results, the conclusions of the article may be correct. However, the authors believe that retraction is appropriate because of the differences in performance of the study, and because the published article does not accurately reflect how all of the animals were infected and treated with 3HP.
Reference
- 1.Foreman TW, Bucşan AN, Mehra S, Peloquin C, Doyle LA, Russell-Lodrigue K, Gandhi NR, Altman J, Day CL, Ernst JD, Blumberg HM, Rengarajan J, Kaushal D. Isoniazid and rifapentine treatment eradicates persistent Mycobacterium tuberculosis in macaques. Am J Respir Crit Care Med. 2020;201:469–477. doi: 10.1164/rccm.201903-0646OC. [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]
