Longitudinal plot of Centiloid value changes over time of all subjects in AIBL with longitudinal scans. Each line connects CL values from unique subjects. The plot is centred on the first change of scanner or tracer, to emphasise potential discontinuities. This is achieved by assigning year zero, for each subject, to their last imaging timepoint before a change of tracer of scanner occurred. Left plot shows CL values measured using the standard method, while the ones in the middle and on the right shows the CL values measured using the NMF2 and NMF6 method, respectively.