Introduction
COVID-19 has become a global health issue especially among chronic hemodialysis patients given their immunocompromised state, pre-existing co- morbidities and regular HD center visits. Thus, this study aims to determine the predictors of 30-day mortality among COVID-19 patients on hemodialysis. Methods. A retrospective cohort of adult chronic hemodialysis patients with COVID-19 from June 1 to August 30, 2020 in National Kidney Transplant Institute.
Methods
A retrospective cohort of adult chronic hemodialysis patients with COVID-19 from June 1 to August 30, 2020 in National Kidney Transplant Institute.
Results
This study included a total of 119 chronic hemodialysis patients. Majority were females (52.1%) non-smoker (84.87%), with mean age of 52 years. Mortality rate was 34% (41/119). Identified factors associated with mortality were older age (OR 1.04 , 95 CI 1.003 to 1.07), diabetes (OR 2.5,95 CI 1.13 to 5.56), higher Charlson’s co-morbidity index ( OR 1.44, 95% CI 1.10 to 1.87), myalgia (OR 3.81, 95% CI 1.04 to 13.89), O2 saturation of < 90% ( OR 3.63, 95% CI 1.19 to 11.1), pulmonary congestion on chest x-ray (OR 2.5045, 95% CI 1.13 to 5.56), elevated LDH (OR 1.002, 95% CI 1.0003 to 1.004) and neutrophils (OR 1.05, 95% CI 1.01 to 1.09) , lower level of lymphocytes (OR 0.93, 95% CI 0.89 to 0.98) and use of mechanical ventilation (OR 5.25, 95% CI 2.23 to 12.33). However, multivariate analysis shows that only diabetes and use of mechanical ventilator were significant predictors of mortality with an OR of 2.52 (95% Cl 1.07 to 5.93) and 5.27 (95% Cl I2.19 to 12.63) respectively.
Conclusions
The presence of diabetes and use of mechanical ventilator were independent predictors of 30-day mortality among chronic HD patients with COVID-19.
No conflict of interest