Massage during hindlimb suspension (HS) alters myofibrillar protein turnover and ribosomal turnover, without any effect on muscle mass or size. Body weight (a), muscle wet weight (b), mean fiber CSA (c), calculated myofibrillar ksyn (d) and myofibrillar kdeg (e), RNA concentration (f), total RNA content (g), and calculated RNA ksyn (g, h) and RNA kdeg (i) from gastrocnemius muscles following 7 days of HS (HS7, n = 8) and HS massaged limb, HSM (n = 8). Values are mean ± SEM. Independent sample t tests were used to determine statistical significance between HS7 and HSM: #p < 0.05, different from HS7