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Conceptual model of the link between sleep deprivation and cardiovascular disease. Sleep deprivation leads to inflammation, oxidative stress, autonomic nervous system dysregulation, and chronobiological disruption, which impair endothelial function and may lead to accelerated vascular aging and cardiovascular disease. SNS, sympathetic nervous system; PNS, parasympathetic nervous system; CVD, cardiovascular disease. Created with BioRender.com
