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. 2021 Apr 15;184(8):2239–2254.e39. doi: 10.1016/j.cell.2021.03.009

Figure S5.

Figure S5

Summary signature trajectories per cancer type, related to Figure 5

The average trajectories for mutation signatures were calculated across tumors of the same cancer type. The color of the line denotes the signature and its width reflects the number of contributing tumors. The trajectories have been centered around the activity at the boundary between clonal and subclonal mutations in order to highlight relative changes in signature activity.