Author Correction: Predicting dissolution and transformation of inhaled nanoparticles in the lung using abiotic flow cells: The case of barium sulphate

Correction to: Scientific Reports https://doi.org/10.1038/s41598-019-56872-3, published online 16 January 2020

This Article contains errors. In the Methods section, under subheading ‘Flow-through abiotic dissolution and transformation’,

“For the lower flow rate, this corresponds to a ratio, SA/V = 0.02 h/cm”.

should read:

“For the lower fowl rate, this corresponds to a ratio, SA/V = 0.02 h/µm”.

In the Results section, under subheading ‘Dynamic abiotic dissolution’,

“If we determine for each sampling interval the instantaneous rates k (in units of ng/cm²/h, Eq. 3) and the instantaneous surface area per volume flow SA/V (in units of h/cm, Eq. 4), hundreds of instantaneous release rates collapse on a single linear relationship, regardless if SA/V was modulated by initial surface area or by flow rate or by gradual dissolution (Fig. 3)”.

should read:

“If we determine for each sampling interval the instantaneous rates k (in units of ng/cm²/h, Eq. 3) and the instantaneous surface area per volume flow SA/V (in units of h/µm, Eq. 4), hundreds of instantaneous release rates collapse on a single linear relationship, regardless if SA/V was modulated by initial surface area or by flow rate or by gradual dissolution (Fig. 3)”.

And,

“The best match of the predicted halftime with the in vivo halftime is obtained for SA/V ratios around 0.01 to 0.03 h/cm”.

should read:

“The best match of the predicted halftime with the in vivo halftime is obtained for SA/V ratios around 0.01 to 0.03 h/µm”.

Furthermore, the x-axis of Figure 3 is incorrectly labeled as “SA/V h/cm”, whereas the correct unit is “SA/V h/μm”. The correct Figure 3 appears below as Figure 1.

Figure 1.

Instantaneous rate evaluation of biodissolution of BaSO₄ in flow-through cells with pH 4.5 PSF media. Each cloud of stepwise rates stems from separate experiment of initial mass M₀ and volume flow V. Five experiments for BaSO₄ (orange) and two for CuO (black). See Table 2 for conventional evaluation (cumulative rates) of the same raw data.