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Association of HFD with gastrointestinal cancers. High fat diet can cause metabolic reprogramming in multiple organs and tissues of the human body with alterations in the content of various regulatory factors. It mainly acts on tumor cells themselves, nearby tissues and tumor microenvironment. The molecules marked in red are upregulated, while green downregulated. GGPPS: Geranylgeranyl diphosphate synthase.
