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Effect of S75, LPC80, SDS and water on the relative natural moisturizing factor (NMF) (a) and urea concentration (b) of human forearm skin in vivo as determined by CRS. The NMF and urea signal intensity is given at different SC depths before the treatment (day one, light grey), and after four days of repeated exposure (day four, H2O in dark grey, S75 in green, LPC80 in blue and SDS in red). Values are means of n = 8 ± SD.
