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PLOS One logoLink to PLOS One
. 2021 Apr 23;16(4):e0250447. doi: 10.1371/journal.pone.0250447

Pooled prevalence and associated factors of health facility delivery in East Africa: Mixed-effect logistic regression analysis

Getayeneh Antehunegn Tesema 1,*, Zemenu Tadesse Tessema 1
Editor: Marwa Farag2
PMCID: PMC8064605  PMID: 33891647

Abstract

Background

Many mothers still give birth outside a health facility in Sub-Saharan Africa particularly in East African countries. Though there are studies on the prevalence and associated factors of health facility delivery, as to our search of literature there is limited evidence on the pooled prevalence and associated factors of health facility delivery in East Africa. This study aims to examine the pooled prevalence and associated factors of health facility delivery in East Africa based on evidence from Demographic and Health Surveys.

Methods

A secondary data analysis was conducted based on the most recent Demographic and Health Surveys (DHSs) conducted in the 12 East African countries. A total weighted sample of 141,483 reproductive-age women who gave birth within five years preceding the survey was included. All analyses presented in this paper were weighted for the sampling probabilities and non-response using sampling weight (V005), primary sampling unit (V023), and strata (V021). The analysis was done using STATA version 14 statistical software, and the pooled prevalence of health facility delivery with a 95% Confidence Interval (CI) was presented using a forest plot. For associated factors, the Generalized Linear Mixed Model (GLMM) was fitted to consider the hierarchical nature of the DHS data. The Intra-class Correlation Coefficient (ICC), Median Odds Ratio (MOR), and Likelihood Ratio (LR)-test were done to assess the presence of a significant clustering effect. Besides, deviance (-2LLR) was used for model comparison since the models were nested models. Variables with a p-value of less than 0.2 in the bivariable mixed-effect binary logistic regression analysis were considered for the multivariable analysis. In the multivariable mixed-effect analysis, the Adjusted Odds Ratio (AOR) with 95% Confidence Interval (CI) were reported to declare the strength and significance of the association between the independent variable and health facility delivery.

Results

The proportion of health facility delivery in East Africa was 87.49% [95% CI: 87.34%, 87.64%], ranged from 29% in Ethiopia to 97% in Mozambique. In the Mixed-effect logistic regression model; country, urban residence [AOR = 2.08, 95% CI: 1.96, 2.17], primary women education [AOR = 1.61, 95% CI: 1.55, 1.67], secondary education and higher [AOR = 2.96, 95% CI: 2.79, 3.13], primary husband education [AOR = 1.19, 95% CI: 1.14, 1.24], secondary husband education [AOR = 1.38, 95% CI: 1.31, 1.45], being in union [AOR = 1.23, 95% CI: 1.18, 1.27], having occupation [AOR = 1.11, 95% CI: 1.07, 1.15], being rich [AOR = 1.36, 95% CI: 1.30, 1.41], and middle [AOR = 2.14, 95% CI: 2.04, 2.23], health care access problem [AOR = 0.76, 95% CI: 0.74, 0.79], having ANC visit [AOR = 1.54, 95% CI: 1.49, 1.59], parity [AOR = 0.56, 95% CI: 0.55, 0.61], multiple gestation [AOR = 1.83, 95% CI: 1.67, 2.01] and wanted pregnancy [AOR = 1.19, 95% CI: 1.13, 1.25] were significantly associated with health facility delivery.

Conclusion

This study showed that the proportion of health facility delivery in East African countries is low. Thus, improved access and utilization of antenatal care can be an effective strategy to increase health facility deliveries. Moreover, encouraging women through education is recommended to increase health facility delivery service utilization.

Background

Maternal and child mortality remains a major public health problem in low-and middle-income countries mainly in Sub-Saharan Africa (SSA) countries [1]. Globally, an estimated 358,000 maternal deaths occur annually, of which 99% occurred in low-and middle-income countries [2]. Even though the maternal mortality rate showed a substantial reduction in high-income countries [3], SSA continues to share the huge burden of global maternal mortality [4].

The World Health Organization (WHO) recommends health facility delivery as a key strategy to reduce maternal and infant mortality [5, 6]. According to the WHO, every pregnant woman should give birth at a health facility but only 48% of SSA births are delivered in a health facility [7, 8]. The lower proportion of health facility delivery is the reflection of poor affordability and accessibility of maternal health care services [9, 10].

Several studies found health facility delivery as a significant predictor responsible for the reduction of maternal and neonatal mortality [11, 12]. However, access to and use of maternal health care services in East African countries remains a major challenge [13, 14]. Previous revealed that maternal education [15], household wealth status [16], maternal occupation [17], husband education [18], distance to health facility [19], residence [20], parity [21], maternal age [20], marital status [22], Antenatal Care (ANC) visit during pregnancy [23, 24], type of gestation [24], and wanted pregnancy [25] were significantly associated factors with health facility delivery.

SSA is projected to have at least 80% of deliveries in health facilities particularly in East African countries, given international success in reducing maternal and neonatal mortality [26]. To improve health facility delivery in East African countries multisectoral collaboration is needed and international stakeholders might work on common factors responsible for the reduction of health facility delivery in different countries.

As far as our literature search is concerned, little is known about the pooled prevalence of health facility delivery and associated factors in East African countries. Therefore, this study aimed at investigating the pooled prevalence and associated factors of health facility delivery in East African Countries based on the most recent Demographic and Health Surveys (DHSs). The findings of this study may aid in the development of evidence-based public health policies to reduce maternal and newborn mortality. Furthermore, since this was a pooled analysis, the study power was increased, allowing for a thorough examination of effect modification within the data.

Methods

Data source and sampling procedures

The DHS data of 12 East African countries (Burundi, Ethiopia, Comoros, Uganda, Rwanda, Tanzania, Mozambique, Madagascar, Zimbabwe, Kenya, Zambia, and Malawi) [27] were used for this study. The DHS is a nationally representative survey that contains data on health and health-related indicators like mortality, morbidity, family planning service utilization, fertility, maternal and child health. The variables were extracted based on literature and appended together to determine the pooled prevalence and associated factors of health facility delivery in East Africa. The DHS employed a two-stage stratified sampling technique to select the study participants. In the first stage, Enumeration Areas (EAs) were randomly selected while in the second stage households were selected. Each country’s survey consists of different datasets including men, women, children, birth, and household datasets, and for this study, we used the women’s datasets (IR file). A total weighted sample of 141,483 reproductive-age women who gave birth in the last five years preceding the survey was included in this study (Table 1).

Table 1. The number of study participants in this study.

Country Number of reproductive age women who gave birth within 5 years preceding the survey Study year
Home delivery Health facility delivery
Burundi 1480 12131 2016/17
Comoros 604 2276 2012
Ethiopia 7809 3213 2016
Kenya 6436 13037 2014
Madagascar 7013 5394 2008/09
Malawi 791 16604 2015/16
Mozambique 285 11192 2011
Rwanda 537 7462 2014/15
Tanzania 3042 7010 2015/16
Uganda 2944 12326 2016
Zambia 3778 9564 2018
Zimbabwe 833 5585 2015

Study variables and measurements

The outcome variable for this study was the place of delivery. For mothers who had more than one child in the last five years preceding the survey, the most recent birth was selected. Place of delivery was categorized into home delivery (when the birth took place at home) or health facility delivery (when the birth took place at the hospital, health center, or health post). The response variable for the ith mother was represented by a random variable Yi with two possible values coded as 1 and 0. So, the response variable of the ith mother Yi was measured as a dichotomous variable with possible values Yi = 1, if ith mother gave birth at the health facility, and Yi = 0 if a mother gave birth at home delivery.

The independent variable retrieved from DHS were country, residence, maternal age, occupational status, women’s educational status, husband’s educational status, wealth status, distance to health care access, ANC visit during the index pregnancy, parity, marital status, preceding birth interval, number of gestation, and wanted pregnancy (Table 2). As the DHSs of the 12 East African countries were not conducted at the same time, we considered the year of the survey as an independent variable by considering 2008 as a reference. The Year of the survey was categorized as 2008 (Madagascar), 2011 (Mozambique), 2012 (Malawi), 2014 (Rwanda and Kenya), 2015 (Malawi, Tanzania, and Zimbabwe), 2016 (Burundi, Uganda, and Ethiopia), and 2018 (Zambia). However, the bi-variable analysis has a p-value of >0.2 and was not eligible for the multivariable analysis.

Table 2. The list of independent variables and their definitions and measurements.

Variable name Definition (measurement)
Country Was coded as 0 “Burundi”, 1 “Comoros”, 2 “Ethiopia”, 3 “Kenya”, 4 “Madagascar”, 5 “Malawi”, 6 “Mozambique”, 7 “Rwanda”, 8 “Tanzania”, 9 “Uganda”, 10 “Zambia” and 11 “Zimbabwe”
Residence Recoded as 0 for rural and 1 for urban
Age of respondent Categorized as 0 for 15–24 years, 1 for 25–34 years and 2 for 35–49 years
Occupational status Women occupation was No “if women were housewife and didn’t working”, and Yes “If a woman were working, she might be self-employed or government employed”
Maternal education status Categorized as; didn’t have formal education, attained primary level of education, and “secondary education and above”
Husband education Categorized as; didn’t have formal education, attained primary level of education, and “secondary education and above”
Wealth status Categorized as; poor “if woman was in poorer and poorest household”, middle and rich “if woman was in richer and richest household”
Preceding birth interval Was categorized as; less than 24 months and ≥ 24 months
ANC visit during pregnancy Categorized as No “if woman didn’t have ANC visit during pregnancy” and Yes “If women had at least one ANC visit during pregnancy”
Distance to reach health facility Categorized as;” A big problem” and “not a big problem”
Parity Number of ever born children after 28 months of gestations categorized as; 1 birth, 2–4 birth, and ≥ 5 births
Number of gestations Categorized as; single and multiple birth
Wanted pregnancy Categorized as Yes “if wanted” and No “if mistimed or unwanted”
Marital status Categorized as; not in union “if never married, divorced, widowed or separated” and in union “if married”

Data management and analysis

We pooled the data from the 12 East African countries together after extracting the variables based on literature. Before any statistical analysis, the data were weighted using sampling weight (V005), primary sampling unit (V023), and strata (V021) to draw a valid conclusion. Data management and analysis were done using STATA version 14 statistical software. The pooled proportion of health facility delivery with the 95% Confidence Interval (CI) was reported using a forest plot. The hierarchical nature of DHS data could violate the independence of observations and equal variance assumption of the traditional logistic regression model. In such cases, advanced statistical models should be fitted to get a reliable estimate. Therefore, a mixed effect logistic regression model (fixed and random effect) was fitted using a cluster variable (V001) as a random variable. The presence of clustering effect was tested using the Intra-class Correlation Coefficient (ICC), Likelihood Ratio (LR) test, and Median Odds Ratio (MOR), and model comparison was made using deviance (-2LLR).

The ICC quantifies the degree of heterogeneity of health facility delivery between clusters (the proportion of the total observed individual variation in health facility delivery that is attributable to between cluster variations) [28].

ICC=ϭ2/(ϭ2+π2/3).

MOR quantifies the variation or heterogeneity in health facility delivery between clusters and is defined as the median value of the odds ratio between the cluster at a high likelihood of health facility delivery and cluster at lower risk when randomly picking out two clusters (EAs) [29].

MOR=exp(2*2*0.6745)MOR=exp(0.95*).

2 indicates that cluster variance.

Variables with a p-value <0.2 in the bi-variable analysis were considered in the multivariable mixed-effect logistic regression analysis. In the multivariable mixed-effect logistic regression model the Adjusted Odds Ratios (AOR) with a 95% Confidence Interval (CI) were reported to declare the statistical significance and strength of association between factors and health facility delivery.

Ethics consideration

Permission to get access to the data was obtained from the measure DHS program online request from http://www.dhsprogram.com.website and the data used were publicly available with no personal identifier.

Results

Socio-demographic and economic characteristics of the respondent

A total of 141,483 live births were included. Of these, 19,563 (13.8%) births were from Kenya, and 110,471 (78.1%) were in rural areas. Besides, 67,704 (47.9%) births were born to mothers aged 25–34 years. More than half (53.7%) of mothers and 41.9% of their husbands attained primary level of education (Table 3).

Table 3. Socio-demographic and economic characteristics of women who gave birth in the last five years in East African countries.

Characteristics Weighted frequency Percentage (%)
Country
Burundi 13,611 9.6
Comoros 2,880 2.0
Ethiopia 11,022 7.8
Kenya 19,563 13.8
Madagascar 12,407 8.8
Malawi 17,395 12.3
Mozambique 11,478 8.1
Rwanda 8,002 5.7
Tanzania 10,052 7.1
Uganda 15,270 10.8
Zambia 13,383 9.5
Zimbabwe 6,418 4.5
Residence
Urban 31,012 21.9
Rural 110,471 78.1
Age in years
15–24 42,167 29.8
25–34 67,704 47.9
≥ 35 31,612 22.3
Women education status
No 33,619 23.8
Primary 75,945 53.7
Secondary and above 31,907 22.5
Husband education
No 25,268 17.9
Primary 59,332 41.9
Secondary and above 56,882 40.2
Women occupational status
No 47,153 33.3
Yes 94,330 66.7
Marital status
Not in union 41,222 29.1
In union 100,261 70.9
Wealth status
Poor 64,368 45.5
Middle 27,586 19.5
Rich 49,529 35.0

Maternal obstetric and health services elated characteristics of the respondent

From a total of 141,483 births, 22,141 (15.7%) of the mothers were primipara, and 4,504 (3.2%) gave multiple births. About 93,360 (66.0%) of the mothers had ANC follow-up during pregnancy and 121,189 (85.7%) were wanted births. Regarding health care access, the majority (57.1%) of the mothers reported distance to reach a health facility as a big problem (Table 4).

Table 4. Maternal obstetric and health service-related characteristics of the respondent.

Characteristics Weighted frequency Percentage (%)
Parity
1 22,141 15.7
2–4 72,858 51.5
≥ 5 46,484 32.8
Number of gestations
Single 136,979 96.8
Multiple 4,504 3.2
Preceding birth interval
< 24 months 19,380 17.9
≥ 24 months 88,934 82.1
Health care access problem
No a big problem 60,714 42.9
A big problem 80,769 57.1
Wanted pregnancy
No 20,294 14.3
Yes 121,189 85.7
ANC visit during pregnancy
No 48,123 34.0
Yes 93,360 66.0

ANC: Antenatal Care.

The pooled prevalence of institutional delivery in East African countries

The pooled proportion of health facility delivery in East African countries was 87.49% [95% CI: 87.34, 87.64], with the highest proportion in Mozambique (97%) and the lowest proportion in Ethiopia (29%) (Fig 1).

Fig 1. The proportion of health facility delivery in East African countries.

Fig 1

Factors associated with health facility delivery

Model comparison

The mixed-effect logistic regression model was the best-fitted model since it had a smaller deviance value (Table 5). Furthermore, the ICC value was 0.22 [95% CI: 0.21, 0.24] and MOR was 2. 52, it indicates if we randomly choose two women from different clusters, a woman from a cluster with higher health facility delivery were 2. 52 times more likely to deliver at a health facility than women from a cluster with a lower proportion of health facility. Besides, the likelihood ratio test was (LR test vs. Logistic model: X2 (01) = 6623.18, p<0.01) which informed that the mixed-effect logistic regression model is the better model over the basic model (Table 5).

Table 5. Model comparison and random effect results.
Parameter Standard logistic regression Mixed-effect logistic regression analysis (GLMM)
LLR -56792 -55922
Deviance 113584 110844
ICC 0.22 [0.21, 0.24]
LR-test LR test vs. logistic model: chibar2(01) = 6623.18 Prob > = chibar2 <0.001
MOR 2.52 [95% CI:2.41, 2.63]
Cluster variance 0.95 [95% CI: 0.86, 1.04]

*LLR; log-likelihood ratio, ICC; Intra-class Correlation Coefficient, MOR; Median Odds Ratio, LR-test; Likelihood Ratio test.

In the multivariable mixed-effect logistic regression model; country, residence, maternal and husband educational status, marital status, wealth status, maternal occupation, distance to the health facility, ANC visit during pregnancy, and wanted pregnancy was significantly associated with health facility delivery.

Mothers in Burundi, Kenya, Comoros, Malawi, Mozambique, Rwanda, Tanzania, Uganda, Zambia and Zimbabwe were 18.04 [AOR = 18.04, 95% CI: 16.65, 19.53], 1.97 [AOR = 1.97, 95% CI: 1.83, 2.12], 6.14 [AOR = 6.14, 95% CI: 5.48, 6.88], 36.99 [AOR = 36.99, 95% CI: 33.69, 40.62], 82.81 [AOR = 82.81, 95% CI: 72.66, 94.36], 22.89 [AOR = 22.89, 95% CI: 20.49, 25.58], 3.63 [AOR = 3.41, 95% CI: 3.18, 3.66], 6.67 [AOR = 6.67, 95% CI: 6.21, 7.16], 3.41 [AOR = 3.41, 95%: 3.18, 3.66] and 6.05 [AOR = 6.05, 95% CI: 5.46, 6.71] times higher odds of having health facility delivery compared to mothers in Ethiopia, respectively. Mothers who lived in urban area were 2.08 times [AOR = 2.08, 95% CI: 1.96, 2.17] higher odds of having health facility delivery than rural mothers.

Mothers who attained primary education, and secondary or above were 1.61 times [AOR = 1.61, 95% CI: 1.55, 1.67] and 2.96 times [AOR = 2.96, 95% CI: 2.79, 3.13] higher odds of having health facility delivery compared to mothers who did not have formal education, respectively. Mothers whose husband had a primary level of education, and secondary education or above were 1.19 times [AOR = 1.19, 95% CI: 1.14, 1.24] and 1.38 times [AOR = 1.38, 95% CI: 1.31, 1.45] higher odds of giving birth at a health facility than mother whose husband did not have formal education, respectively.

The odds of health facility delivery utilization by women who were in union were 1.23 times [AOR = 1.23, 95% CI: 1.18, 1.27] higher than women who were not in union, and mothers who had occupation were 1.11 times [AOR = 1.11, 95% CI: 1.07, 1.15] higher odds of having health facility than women who did not have an occupation. Women from a household with middle and rich wealth status were 1.36 [AOR = 1.36, 95% CI: 1.30, 1.41], and 2.14 [AOR = 2.14, 95% CI: 2.04, 2.23] times higher odds of health facility delivery than women from a poor household, respectively. The odds of health facility delivery among mothers who had a big health care access problem were decreased by 24% [AOR = 0.76, 95% CI: 0.74, 0.79] compared to women where health care access was not a big problem.

Mothers who had ANC follow-up during pregnancy had 1.54 [AOR = 1.54, 95% CI: 1.49, 1.59] times higher odds of health facility delivery than women who did not have ANC visit. The odds of health facility delivery among mothers who had two to four births, and five and above were decreased by 44% [AOR = 0.56, 95% CI: 0.55, 0.61] and 62% [AOR = 0.38, 95% CI: 0.35, 0.40] compared to women who were primipara, respectively. Mothers with multiple gestations were 1.83 [AOR = 1.83, 95% CI: 1.67, 2.01] times higher odds of delivering at a health facility compared to mothers with single gestation, and mothers whose pregnancy were wanted to have 1.19 [AOR = 1.19, 95% CI: 1.13, 1.25] times increased odds of health facility delivery (Table 6).

Table 6. Multivariable mixed-effect logistic regression analysis of determinants of health facility delivery in East African countries.
Variable Place of delivery Crude Odds Ratio (COR) with 95% CI Adjusted Odds Ratio (AOR) with 95% CI
Home Health facility
Country
Burundi 1480 12131 16.82 [15.67, 18.05] 18.04 [16.65, 19.53]
Comoros 604 2276 5.56 [5.01, 6.16] 1.97 [1.83, 2.12]
Ethiopia 7809 3213 1 1
Kenya 6437 13037 3.38 [3.19, 3.59] 6.14 [5.48, 6.88]
Madagascar 7013 5394 1.48 [1.40, 1.57] 1.01 [0.94, 1.08]
Malawi 791 16604 50.31 [46.08, 54.93] 36.99 [33.69, 40.62]
Mozambique 286 11192 77.15 [68.05, 87.47] 82.81 [72.66, 94.36]
Rwanda 537 7462 29.47 [26.63, 32.62] 22.89 [20.49, 25.58]
Tanzania 3042 7010 4.75 [4.47, 5.05] 3.63 [3.37, 3.90]
Uganda 2945 12326 7.78 [7.34, 8.25] 6.67 [6.21, 7.16]
Zambia 3778 9564 5.31 [5.01, 5.62] 3.41 [3.18, 3.66]
Zimbabwe 833 5585 14.25 [13.02, 15.60] 6.05 [5.46, 6.71]
Residence
Urban 2997 22977 3.55 [3.41, 3.70] 2.08 [1.96, 2.17]
Rural 32557 77818 1 1
Maternal education status
No 13920 19679 1 1
Primary 18482 57388 2.54 [2.47, 2.62] 1.61 [1.55, 1.67]
Secondary and above 3147 28722 7.16 [6.84, 7.48] 2.96 [2.79, 3.13]
Husband education status
No 9797 15462 1 1
Primary 15623 43677 2.10 [2.04, 2.17] 1.19 [1.14, 1.24]
Secondary and above 10134 46657 3.25 [3.14, 3.37] 1.38 [1.31, 1.45]
Respondent age in years
15–24 8908 33,219 1 1
25–34 17026 50611 0.78 [0.76, 0.81] 1.05 [0.97, 1.10]
≥35 9620 21965 0.60 [0.58, 0.62] 1.05 [0.99, 1.11]
Marital status
Not in union 8256 32943 1 1
In union 27298 72852 0.63 [0.61, 0.65] 1.23 [1.18, 1.27]
Maternal occupation status
No 12774 34277 1 1
Yes 22780 71518 1.26 [1.23, 1.30] 1.11 [1.07, 1.15]
Wealth status
Poor 22262 42031 1 1
Middle 7075 20485 1.83 [1.77, 1.90] 1.36 [1.30, 1.41]
Rich 6217 43279 4.43 [4.28, 4.58] 2.14 [2.04, 2.23]
Distance to health care access
Not a big problem 19282 66007 1 1
Big problem 16272 39788 0.71 [0.69, 0.73] 0.76 [0.74, 0.79]
ANC visit during pregnancy
No 17064 30943 1 1
Yes 18490 74852 2.27 [2.22, 2.33] 1.54 [1.49, 1.59]
Parity
1 2748 19390 1 1
2–4 16106 56683 0.50 [0.48, 0.52] 0.56 [0.55, 0.61]
≥ 5 16701 29721 0.25 [0.24, 0.27] 0.38 [0.35, 0.40]
Number of gestations
Single 34689 102167 1 1
Multiple 865 3628 1.47 [1.36, 1.59] 1.83 [1.67, 2.01]
Wanted pregnancy
No 6661 14031 1 1
Yes 29394 91763 1.36 [1.31, 1.41] 1.19 [1.13, 1.25]

Discussion

In East Africa, the proportion of health facility delivery was 87.49%. This was higher than a study reported in SSA [8]. The possible explanation could be due to the difference in the study period and the number of countries included in the study. It was significantly varied across counties, ranging from 29% in Ethiopia to 97% in Mozambique. This may be because of the lack of sufficient medical care and human resources in the Ethiopian health system to satisfy more than 100 million Ethiopians [30].

In the multivariable mixed effect binary logistic regression analysis; country, residence, maternal education status, husband education status, marital status, household wealth status, ANC visit during pregnancy, wanted pregnancy, health care access problem, parity, number of gestations, and occupational status were significantly associated with health facility delivery. In this study, the mother’s place of residence was significantly associated with health facility delivery. Urban mothers had higher odds of having health facility delivery than rural mothers. This is consistent with studies reported in SSA [31] and Africa [32]. This might be due to the residential disparity in availability and accessibilities of maternal health care services [33, 34]. Also, in urban areas maternal education [35], access to maternal health services [36], and access to information is relatively good than rural mothers [17, 34]. Furthermore, evidence suggests that the majority of women in rural areas preferred to give birth at home with traditional birth attendants for the sake of privacy and social acceptance than urban mothers [6].

Women who attained primary education or higher were more likely to give birth at a health facility than women with no formal education. It was in line with studies reported in Sub-Saharan Africa [31], China [37], and the WHO Global survey [38]. This may be because educated mothers would have a better understanding of the risks of childbirth, the provision of maternal health care, and the value of health facility delivery for newborns and their health [39]. In addition, maternal education plays a significant role in enhancing the mother’s health care decision-making autonomy [40]. Besides, husband education was a significant predictor of health facility delivery, women whose husbands completed primary education or higher were more likely to deliver in the health facility than women whose husbands did not have formal education. It was supported by previous studies reported in Pakistan [18], Nigeria [41], Nepal [42], and Sub-Saharan Africa [43]. This might be since educated husbands can empower women in making health care decisions and get involved in making birth preparedness and complication preparedness plan would also increase the center’s service use [44]. Besides, educated men would have better access to information about the importance of health facility delivery and complications of home delivery to the mother and their baby [45], and in fact, education leads to better health awareness, which may sensitize the mother to decide and utilize maternal health care services [46].

Being married had higher odds of health facility delivery than women who were not in a union. It was consistent study findings in Kenya [47] and Nigeria [41]. This might be due to married women had spousal support in making health care decisions towards maternal health service utilization as well as economic and social support [48]. Besides, when women pregnant without being in union are possibly less motivated to give birth at a health facility due to community stigmatization and marginalization [49].

Household wealth status and women’s occupation were found to be significant predictors of health facility delivery. Women who were from the household with middle and rich wealth stratus were more likely to give birth at a health facility than women who were from poor households. It was consistent with the study findings in Nepal [50] and SSA [31]. In some African countries such as Ethiopia, Tanzania, and Kenya, even though maternal health services are offered free of charge by law or pro-poor fee exemption [51], indirect costs such as transportation costs and other opportunity costs for mothers and newborns prohibit mothers from using health facility delivery from poor families [52].

In this study, parity was an important predictor of health facility delivery. Primiparous women had higher odds of health facility delivery than multi-parous women. This finding was supported by previous studies [20, 21, 41], it could be because primigravida women feel that they are more prone to complications during delivery and seek maternity care services [53]. Besides, Multiparous women often choose to give birth at home for the sake of privacy and feel they will not be complicated as they are familiar with childbirth [54]. Besides, multiparous women are the least likely to seek maternity care services due to greater confidence and cumulative experience of delivery [54]. Having an ANC visit during pregnancy increases the likelihood of health facility delivery than women who did not have ANC visits during pregnancy. It was consistent with previous studies [18, 55], this is attributed to the assumption that mothers who have ANC visit during pregnancy may increase women’s knowledge of birth preparedness and risks of pregnancy and childbirth, which may increase the possibility of getting delivery at health facilities [56, 57]. Furthermore, the use of ANC may signify the availability of a nearby health care service, which may also provide delivery care, and ANC providers should educate and advise women and their families on danger signs through a process to create individual birth plans that can prepare them for institutional delivery and make timely decisions in the event of an emergency to pursue health care [17]. Mothers whose pregnancy was wanted to have higher odds of health facility delivery than an unwanted pregnancy. When pregnancy is wanted, pregnant women may have ANC visits and regular medical check-ups, which could increase their knowledge of potential complications and safe delivery practices, ultimately encouraging them to pursue health facility delivery to get a healthy child [58].

The other most significant predictor of health facility delivery in this study was the type of gestation. Mothers who have multiple gestations had higher odds of health facility delivery than singletons. This was consistent with prior studies [24, 59], This may be because mothers with multiple gestations are at greater risk of complications related to pregnancy, such as obstructed labor, birth asphyxia, antepartum hemorrhage, preeclampsia, and postpartum hemorrhage [60], which may encourage women to give birth in a health facility. Besides, the health care access problem was associated with a lower likelihood of health facility delivery. This could be due to the reason that the health care access problem is the main factor for home delivery, it highlights that there is a need to make maternal health care services available and accessible to the community.

Though enhancing health facility delivery is identified as the best strategy to achieve the Sustainable Development Goal (SDG) 3 of ending preventable maternal mortality and reducing Maternal Mortality Ratio (MMR) to fewer than 70 maternal death per 100,000 live births by 2030, health facility delivery was low in East African countries. Therefore, the stakeholders, governmental and non-governmental organizations should promote health facility delivery through enhancing mothers’ ANC service utilization, and promoting women’s education. Besides, special emphasis should be given to rural residents and poor households to improve health facility delivery. Even though the World Health Organization’s recommendation for every pregnant woman to give birth at the health facility and by a skilled birth attendant, the rate remains low in East African countries. This may be because women need effective support to decrease home delivery practice. It is therefore important to improve women, family, and community awareness about institutional delivery, ANC follows up, and knowledge of danger signs of pregnancy.

Strength and limitations

The strength of this study was that it was based on a weighted large, nationally representative data set and could have adequate statistical power to detect the true association of factors with health facility delivery. Besides, the study is done using an advanced model to take into account the clustering effect (mixed-effect logistic regression) to get reliable standard error and estimate. However, the study finding is interpreted in light of limitations. First, as with other cross-sectional studies, the temporal relationship can’t be established. Second, the DHS didn’t incorporate information about health care availability and accessibility like distance to the health facility, and the quality of maternal health services provided which might influence the use of health facility delivery of reproductive-age women. Also, since data was collected from self-report from respondents there may be a possibility of social desirability bias.

Conclusions

This study found that health facility delivery in East Africa was far below to achieve a sustainable development goal. Country, urban residence, maternal education, husband education, multiple gestations, wanted pregnancy, ANC visit during pregnancy, middle and rich wealth status, having an occupation, and married marital status was positively associated with health facility delivery. Whereas, multiparty, and big health care access problem was negatively associated with health facility delivery. Thus, improved access and utilization of antenatal care can be an effective strategy to increase health facility deliveries. Moreover, encouraging women through education is recommended to increase health facility delivery service utilization.

Acknowledgments

We greatly acknowledge MEASURE DHS for granting access to the East African DHS data sets.

Abbreviations

ANC

Antenatal Care

AOR

Adjusted Odds Ratio

CI

Confidence Interval

DHS

Demographic Health Survey

GLMM

Generalized Linear Mixed Models

ICC

Intra-class Correlation Coefficient

LLR

log-likelihood Ratio

LR

Likelihood Ratio

MOR

Median Odds Ratio

SSA

Sub-Saharan Africa

WHO

World Health Organization

Data Availability

The underlying data is available online from www.measuredhs.com.

Funding Statement

The author(s) received no specific funding for this work.

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Decision Letter 0

Nancy Beam

28 Sep 2020

PONE-D-20-19261

Pooled prevalence and determinants of health facility delivery in East Africa: A pooled analysis of Demographic and Health Surveys

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Reviewer #1: I would like to thank the authors for their submission on this important topic. In summary, this manuscript requires assistance from a native English speaker to improve the grammar and sentence structure, as well as the organization of the material. I found these issues to be rather distracting while reading the manuscript. Secondly, I have made suggestions for improving different sections of the manuscript below. I have also included some suggested rewrites for some statements in the manuscript.

Introduction

The authors did not make a clear case for the importance of a pooled study. Decision-making is typical at national and sub-national levels in individual countries so it is not clear what a pooled prevalence study adds. How would a study like this influence policy within each country? The question of “why is this important” is not addressed.

Methods

Data Source: Please provide a citation for your data sources, specifically, the DHS program

Please provide a description of your dataset. How many women responded to each question by country? How many responded “Yes” or “No”? How much missing data did you have? What was the DHS year for each country’s dataset? How did you decide on the independent variables?

Please conduct sensitivity analysis to investigate the impact of having more participants from Kenya in this. How does this influence the study findings?

Discussion

This section needs to be better organized. The discussion should be used to summarize the study findings, discuss its implications and make recommendations. What does the study findings imply for progress towards the 2030 SDGs? What can be done to improve health facility delivery in East Africa based on the study findings? While it is important to highlight how the study findings is related to existing literature, it is important that actionable insights are drawn from the study

Lines 212 – 214: It seems the aims of the study as stated here differs from what was declared in the introduction

Suggestions for improving grammar

Lines 54 – 56: Maternal mortality has decreased significantly in developed countries (3) but SSA continued to account for 66% of maternal deaths worldwide

Suggestion: “continued” should be continues

Lines 58 – 59: As key strategies for reducing maternal and infant mortality, the World Health Organization (WHO) recommended a health facility delivery

Suggested rewrite: The World Health Organization recommends health facility delivery as a key strategy for reducing maternal and infant mortality

Lines 63 – 64: The proportion of institutional delivery serves as a measure of progress towards maternal and infant mortality reduction

Suggested rewrite: The proportion of institutional delivery serves as a measure of progress towards reductions in maternal and infant mortality.

Lines 64 – 67: The East African countries that include Burundi, Ethiopia, Comoros, Uganda, Rwanda, Tanzania, Mozambique, Madagascar, Zimbabwe, Kenya, Zambia, and Malawi are among the world's poor countries with accessibility and affordability of maternal health care services

Suggested rewrite: Globally, East African countries rank the lowest for affordability and accessibility of maternal health services, and have the greatest share of maternal deaths.

Line 175: “was” should be “were”

Reviewer #2: Reviewer feedback

The authors make an important contribution to our understanding of the factors associated with health facility delivery. The main advantages of this paper are 1) it uses pooled DHS data from multiple countries, which is a new approach, and 2) the methodological approach is robust and appropriate. The paper is very well organized and written is terms of structure, flow of ideas and coherence. However, there are numerous language errors and awkward sentences so the paper could benefit from professional editing.

Detailed comments

1. I think pooling DHS data is an important contribution of this paper. However, the authors do not say this approach is useful or worth pursing in the paper. The authors should explicitly and clearly explain this.

2. It is not clear what are the years for these datasets? Are you all for the same year or difference years? And what did the authors do to make sure that the time dimension is not influencing the results?

3. There are issues with merging DHS datasets from different countries related to the use of DHS instrument itself in each country and data consistency issues that must be at least covered in the limitations section

4. Some of the statements are missing a source/reference. For example, Page 10, line 215, the reference for the mentioned study is not listed.

5. Page 11, line 246, “The potential reason could be that educated husbands can include women making decisions about the use of maternal health services in health care.” The way this is written implies that decisions about women’s health are naturally the responsibility of men but educated men include women in the decision. I do not think this is what the authors intended to say so they should write this point more carefully.

6. I found that the weakest part of the paper are the discussion and more so the conclusions. The discussion should go beyond simply saying when the results agree and disagree with other studies.

7. The study finds that “country, urban residence, maternal education, husband education, multiple gestations, wanted pregnancy, ANC visit during pregnancy, middle and rich wealth status, having an occupation, and married marital status was positively associated with health facility delivery.” These results are hardly surprising; this is what we know already. The study only confirms what we already know. The authors should highlight how they believe this study adds value and contributes to better understanding.

8. The conclusions are quite vague and not helpful. The authors should discuss policy implications of their work. “Therefore, the governmental and non-governmental organizations should scale up their programs to encourage women education and ANC service utilization for pregnant women.” This statement is completely generic and unhelpful. Why should non-governmental organizations listen? An adequate well-written policy implication section should be included in the conclusions section.

9. Language

• Page 2, line 17 – “But still….” Is an informal way to express this idea

• Page 3, line 44- “ the government and non-governmental…. what? – awkward sentence”

• Page 10, line 218-219, “This could be due to the Ethiopian health system suffers from a lack of adequate medical care and human resources to meet more” There are grammatical errors in this sentence, and it seems like shortage or inadequate supply would be more accurate than “lack” which means there are none.

• Page 12, line 252, “women who were not in union” this is not a clear way to sayunmarried.

• Page 12, line 254 “This might be due to married women had spousal support in making health care decisions towards maternal health service utilization as well as economic and social support” grammatical errors.

• Page 14, line 297, it is better not to say “can’t” and “didn’t” – can not and did not

• Page 14, line 303, “showed that there is the health facility delivery utilization by the reproductive age women has been significantly varied across countries in East Africa.” Sente

**********

6. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

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Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #1: Yes: Ifeoma D Ozodiegwu

Reviewer #2: No

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

Attachment

Submitted filename: review comments_healthfacility_PLosONE.docx

PLoS One. 2021 Apr 23;16(4):e0250447. doi: 10.1371/journal.pone.0250447.r002

Author response to Decision Letter 0


26 Oct 2020

Point by point response

Manuscript Title: Pooled prevalence and determinants of health facility delivery in East Africa: A pooled analysis of Demographic and Health Surveys/ Pooled prevalence and associated factors of health facility delivery in East Africa: A pooled analysis of Demographic and Health Surveys

Manuscript ID: PONE-D-20-19261

Dear editor/reviewers:

Thank you for giving us the chance to revise the manuscript. The comments are too imperative, which are important for improving the quality of our paper. We have addressed all of the concerns raised and these modifications are also incorporated in the revised manuscript.

Response to reviewers’ comment

1. I would like to thank the authors for their submission on this important topic. In summary, this manuscript requires assistance from a native English speaker to improve the grammar and sentence structure, as well as the organization of the material. I found these issues to be rather distracting while reading the manuscript. Secondly, I have made suggestions for improving different sections of the manuscript below. I have also included some suggested rewrites for some statements in the manuscript.

Authors’ response: Thank you for the comments. We extensively modified the sentence structure and any typographical errors with the help of experts. Besides, we consider your suggestions as well as your constructive comments and we modified the manuscript. (See the revised manuscript)

2. Introduction, the authors did not make a clear case for the importance of a pooled study. Decision-making is typical at national and sub-national levels in individual countries so it is not clear what a pooled prevalence study adds. How would a study like this influence policy within each country? The question of “why is this important” is not addressed.

Authors’ response: Thank you reviewer for the comments. As you stated very well decision-making is typical at the national and sub-national level in each country, considering this issue we have reported the prevalence of health facility delivery for each country as well we have reported the prevalence of health facility delivery at the East Africa level to know what health facility level looks like as compared to other regions. Just the main thing we use pooled analysis is not only to know the pooled prevalence but also to increase the statistical power of the study to detect the true effect of independent variables. As you know when we pool the DHSs of the 12 East African countries, the sample size increases and could result in the corresponding improvement in the power of the study and we would get valid evidence. Besides, the DHS of the 12 East African countries uses similar study design and sampling procedures, and therefore the estimate we got in this study is reliable to use for policymakers. (See the background and Discussion section, line 98-101, and line 246-250, page 5 and 11)

3. Methods, data Source: Please provide a citation for your data sources, specifically, the DHS program

Authors’ response: Thank you reviewer for the comments. We cited the DHS program address. (See the revised manuscript, line 107, and page 5)

4. Please provide a description of your dataset. How many women responded to each question by country? How many responded “Yes” or “No”? How much missing data did you have? What was the DHS year for each country’s dataset? How did you decide on the independent variables?

Authors’ response: Thank you reviewer for the comments. There was no missing as we kept our study participants as women who gave birth within five years preceding the survey and present the study sample in each country through the table. We retrieved the independent variables from the DHSs based on literature. Besides, we select variables for the final model using the LASSO and Elastic Net method in addition to the bivariable analysis. (See Table 1)

5. Please conduct a sensitivity analysis to investigate the impact of having more participants from Kenya on this. How does this influence the study findings?

Authors’ response: Thank you reviewer for the comments. We reported the prevalence using forest plots but the study was not a meta-analysis. This study was a pooled data analysis, just to know the prevalence of health facility delivery and associated factors in East Africa and in each country based on the DHSs data that have the same design as well as sampling procedure. So, our aim is not to get the pooled estimate like in metanalysis and the I-squared reported in this is not to show the heterogeneity. Here in this study, the unit of analysis was individuals but not studies like a meta-analysis. Overall, our study aimed to use to pooled DHS data to increase the statistical power of the study to detect the true effect of the variables. Besides, we aimed to assess whether health facility delivery utilization has been varied across countries in East Africa, and if we remove Kenya, we can not answer it. Furthermore, we have checked whether the estimates varied with the presence and absence of Kenya, and the result showed there was a difference in the prevalence of health facility delivery but not in the OR.

6. Discussion, this section needs to be better organized. The discussion should be used to summarize the study findings, discuss its implications and make recommendations. What does the study findings imply for progress towards the 2030 SDGs? What can be done to improve health facility delivery in East Africa based on the study findings? While it is important to highlight how the study findings is related to existing literature, it is important that actionable insights are drawn from the study, Lines 212 – 214: It seems the aims of the study as stated here differs from what was declared in the introduction.

Authors’ response: Thank you reviewer for the comments. We summarize the study findings and their implications in the Discussion section of the manuscript. Besides, we compare our findings with previous studies and we wrote out the possible explanations. (See the revised manuscript)

7. Suggestions for improving grammar

- Lines 54 – 56: Maternal mortality has decreased significantly in developed countries (3) but SSA continued to account for 66% of maternal deaths worldwide

Suggestion: “continued” should be continues

Authors’ response: Thank you reviewer we modified it. (See the Background section, line 67, page4)

- Lines 58 – 59: As key strategies for reducing maternal and infant mortality, the World Health Organization (WHO) recommended a health facility delivery

Suggested rewrite: The World Health Organization recommends health facility delivery as a key strategy for reducing maternal and infant mortality

Authors’ response: Thank you reviewer for the comments. We rewrite it. (See the background section, line 70-71, page 4)

- Lines 63 – 64: The proportion of institutional delivery serves as a measure of progress towards maternal and infant mortality reduction

Suggested rewrite: The proportion of institutional delivery serves as a measure of progress towards reductions in maternal and infant mortality.

Authors’ response: Thank you reviewer for the comments. We rewrite it. (See the Background section, line 71-72, page 4)

- Lines 64 – 67: The East African countries that include Burundi, Ethiopia, Comoros, Uganda, Rwanda, Tanzania, Mozambique, Madagascar, Zimbabwe, Kenya, Zambia, and Malawi are among the world's poor countries with accessibility and affordability of maternal health care services

Suggested rewrite: Globally, East African countries rank the lowest for affordability and accessibility of maternal health services, and have the greatest share of maternal deaths.

Authors’ response: Thank you reviewer for your suggestion. We rewrite it. (See Background section, line 77-79, page 4)

- Line 175: “was” should be “were”

Authors’ response: Thank you reviewer for the suggestion. We rewrite it. (see the discussion section, line 263, page 12)

Response to Reveiwer#2

The authors make an important contribution to our understanding of the factors associated with health facility delivery. The main advantages of this paper are 1) it uses pooled DHS data from multiple countries, which is a new approach, and 2) the methodological approach is robust and appropriate. The paper is very well organized and written is terms of structure, flow of ideas and coherence. However, there are numerous language errors and awkward sentences so the paper could benefit from professional editing.

Authors’ response: Thank you, reviewer. We extensively modified the body of the manuscript for any language error with the help of language experts at the University of Gondar. (See the revised manuscript)

1. I think pooling DHS data is an important contribution of this paper. However, the authors do not say this approach is useful or worth pursing in the paper. The authors should explicitly and clearly explain this.

Authors’ response: Thank you reviewer for your comments to strengthen our paper. We used pooled data analysis for this study. As you stated, pooling DHS data is very important to increase the statistical power of the study to detect the true effect of the independent variables in addition to providing the prevalence of health facility delivery at the East Africa level as well as in each country. This is important for WHO as well for international programs to design targeted interventions. Besides, we used the advanced statistical analysis technique that was multilevel analysis, this could be helpful to provide valid evidence for policymakers and program planners. We stated in the background and discussion section in a short and precise manner. (See the background and Discussion section, line 98-101, and line 246-250, page 5 and 11)

2. It is not clear what are the years for these datasets? Are you all for the same year or difference years? And what did the authors do to make sure that the time dimension is not influencing the results?

Authors’ response: Thank you reviewer for the comments. The years for these datasets were from 2008/09 to 2018, and to detect whether the time dimension was influencing the study results by categorizing years into two as 0 “If the study period ≤2015” and 1 “if the study period was > 2015” the categorization was based on the millennium development goal as during MDG and during SDG. But unfortunately, it was not eligible for the final model as it has a p-value greater than 0.2 in the bi-variable analysis. Besides, we have done a chi-square test whether the year of the survey was significantly associated with health facility delivery but it was not significant. (See Table 1)

3. There are issues with merging DHS datasets from different countries related to the use of DHS instrument itself in each country and data consistency issues that must be at least covered in the limitations section.

Authors’ response: Thank you reviewer for the comments. The DHS uses similar measurements for the variables in each country and the data are consistent. We have checked the consistency of measurement of variables before we do the analysis and the variables were consistently measured. Besides, the variables we have used in this study may not need that much-sophisticated measurement as it was self-report from the respondents through interviews. As a limitation, we have stated the issues related to the study design used in DHS and the variables missed in DHS but that was important for this study.

4. Some of the statements are missing a source/reference. For example, on Page 10, line 215, the reference for the mentioned study is not listed.

Authors response: Thank you reviewer for the comments. We provide an appropriate citation for the statements we have used in the manuscript. (See the revised manuscript)

5. Page 11, line 246, “The potential reason could be that educated husbands can include women making decisions about the use of maternal health services in health care.” The way this is written implies that decisions about women’s health are naturally the responsibility of men but educated men include women in the decision. I do not think this is what the authors intended to say so they should write this point more carefully.

Authors’ response: Thank you reviewer for the comments. We rewrite it. (see the Discussion section, line 283-289, page 13)

6. I found that the weakest part of the paper is the discussion and more so the conclusions. The discussion should go beyond simply saying when the results agree and disagree with other studies

Authors’ response: Thank you reviewer for the comments. We rewrite it extensively. (See the revised manuscript)

7. The study finds that "country, urban residence, maternal education, husband education, multiple gestations, wanted pregnancy, ANC visit during pregnancy, middle and rich wealth status, having an occupation, and married marital status was positively associated with health facility delivery." These results are hardly surprising; this is what we know already. The study only confirms what we already know. The authors should highlight how they believe this study adds value and contributes to a better understanding.

Authors’ response: Thank you reviewer for the comments. We had stated in the discussion and conclusion section of the study. This study adds both statistical and public health value. Regarding statistical value, this study was done by pooling DHSs data conducted in 12 East African countries and this increases the statistical power of the study to detect the true effect size. Besides, we applied the mixed-effect analysis as since DHS data has hierarchical nature, therefore, the findings are reliable as it was analyzed using the advanced model. Regarding the public health aspect, this study was conducted at the East Africa level and we get the pooled estimate and the pooled estimate of health facility delivery in East Africa and the prevalence of health facility delivery for each country as well as factors associated with it. These findings are reliable as it was based on weighted large data using the advanced model and this could help to design evidence-based international and national public health programs.

8. The conclusions are quite vague and not helpful. The authors should discuss policy implications of their work. “Therefore, the governmental and non-governmental organizations should scale up their programs to encourage women education and ANC service utilization for pregnant women.” This statement is completely generic and unhelpful. Why should non-governmental organizations listen? An adequate well-written policy implication section should be included in the conclusions section.

Authors’ response: Thank you reviewer for the comments. We rewrite it. (See the conclusion section, line 360-374, page 16)

9. Language

• Page 2, line 17 – “But still….” Is an informal way to express this idea

• Page 3, line 44- “ the government and non-governmental…. what? – awkward sentence”

• Page 10, line 218-219, “This could be due to the Ethiopian health system suffers from a lack of adequate medical care and human resources to meet more” There are grammatical errors in this sentence, and it seems like shortage or inadequate supply would be more accurate than “lack” which means there are none.

• Page 12, line 252, “women who were not in union” this is not a clear way to sayunmarried.

• Page 12, line 254 “This might be due to married women had spousal support in making health care decisions towards maternal health service utilization as well as economic and social support” grammatical errors.

• Page 14, line 297, it is better not to say “can’t” and “didn’t” – can not and did not

• Page 14, line 303, “showed that there is the health facility delivery utilization by the reproductive age women has been significantly varied across countries in East Africa.” Sente

Authors’ response: Thank you reviewer for your constructive comments. We extensively modified the document by taking into your comments. (See the revised manuscript)

Attachment

Submitted filename: Point by point response.docx

Decision Letter 1

Marwa Farag

12 Jan 2021

PONE-D-20-19261R1

Pooled prevalence and associated factors of health facility delivery in East Africa: A pooled analysis of Demographic and Health Surveys

PLOS ONE

Dear Dr. Tesema,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by February 20. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:

  • A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: http://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols

We look forward to receiving your revised manuscript.

Kind regards,

Marwa Farag

Academic Editor

PLOS ONE

The following concerns were not adequately addressed by the author:

The authors addressed some of the points raised by the reviewers adequately. However, some key points and concerns were not addressed in the revised draft.

1. What did the authors do to make sure that the time dimension is not influencing the results?

The authors stated that the DHS dataset years spanned from 2008 to 2018. This is a long time period and they do not provide convincing evidence that year of study did not matter. The approach they adopted of picking a random year 2015 and testing it whether there is a significant difference before or after is not sufficient. Have you considered other approaches, including year fixed effects (dummies) or any other appropriate approach?

2. What is the justification for adopting this design of a pooled analysis?

The statistical justification for adopting the pooled design is not sufficient. The DHS datasets are already large enough. The justification should include meaningful reasons, such as understanding factors common or that apply across the region. The authors should be able to answer why it is a good idea to do this work and the answer cannot just be to increase statistical power.

3. Language use in the manuscript is still inadequate. Here are examples from the abstract:

Page 2, line 18 – “but still home delivery is common in” – This is an informal way to say this.

Page 3, line 53 - “Was far below to achieve” – Sentence structure issue

The entire conclusions section is not well written. There are many awkward sentences such as: “Moreover, special attention should be needed for poor”

This manuscript needs to edited by a professional editor. It does not matter if the editor is a native english speaker or not. It needs professional editing by a professional.

[Note: HTML markup is below. Please do not edit.]

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

PLoS One. 2021 Apr 23;16(4):e0250447. doi: 10.1371/journal.pone.0250447.r004

Author response to Decision Letter 1


26 Feb 2021

Point by point response for editors/reviewers comments

PLOS ONE Journal

Manuscript title: Pooled prevalence and associated factors of health facility delivery in East Africa: A pooled analysis of Demographic and Health Surveys/ Pooled prevalence and associated factors of health facility delivery in East Africa: Mixed-effect logistic regression analysis

Manuscript ID: PONE-D-20-19261R1

Dear editor/reviewer.

Dear all,

We would like to thank you for these constructive, building, and improvable comments on this manuscript that would improve the substance and content of the manuscript. We considered each comment and clarification questions of editors and reviewers on the manuscript thoroughly. Our point-by-point responses for each comment and question are described in detail on the following pages. Further, the details of changes were shown by track changes in the supplementary document attached.

Response to Editors’ comment

1. The following concerns were not adequately addressed by the author:

The authors addressed some of the points raised by the reviewers adequately. However, some key points and concerns were not addressed in the revised draft.

Authors’ response: Thank you for the comments, we have addressed all the comments. (See the revised manuscript)

2. What did the authors do to make sure that the time dimension is not influencing the results?

The authors stated that the DHS dataset years spanned from 2008 to 2018. This is a long period and they do not provide convincing evidence that year of study did not matter. The approach they adopted of picking a random year 2015 and testing it whether there is a significant difference before or after is not sufficient. Have you considered other approaches, including year fixed effects (dummies) or any other appropriate approach?

Authors’ response: Thank you for the comments. We run the model considering the year of the survey as a fixed effect (dummies) considering 2008 as a reference but it was not eligible for the final analysis as it has a p-value < 0.2.

We generate a variable year of the survey as, 2008 (Madagascar), 2011 (Mozambique), 2012 (Malawi), 2014 (Rwanda and Kenya), 2015 (Malawi, Tanzania, and Zimbabwe), 2016 (Burundi, Uganda, and Ethiopia), and 2018 (Zambia). Descriptively the prevalence over time was ranging from 44.5% to 72.5% showed a change over time but the regression was not significant when we considered it as a dummy variable and adjusted with the presence of other predictors. If there is a need to report in the manuscript, we are ready to incorporate it.

3. What is the justification for adopting this design of a pooled analysis?

The statistical justification for adopting the pooled design is not sufficient. The DHS datasets are already large enough. The justification should include meaningful reasons, such as understanding factors common or that apply across the region. The authors should be able to answer why it is a good idea to do this work and the answer cannot just be to increase statistical power.

Authors’ response: Thank you for the comments. We provide additional justification considering the direction you provide us. Previously we justified it with respect to the statistical significance of pooled analysis but now based on your critical suggestion we justify the clinical implications of a pooled analysis. (See the revised manuscript)

4. Language use in the manuscript is still inadequate. Here are examples from the abstract:

Page 2, line 18 – “but still home delivery is common in” – This is an informal way to say this.

Page 3, line 53 - “Was far below to achieve” – Sentence structure issue

The entire conclusions section is not well written. There are many awkward sentences such as: “Moreover, special attention should be needed for poor”

This manuscript needs to edited by a professional editor. It does not matter if the editor is a native english speaker or not. It needs professional editing by a professional.

Authors’ response: Thank you for the comments. We extensively modified the entire document with the help of language experts at the university. (See the revised manuscript)

Attachment

Submitted filename: Point by point response.docx

Decision Letter 2

Marwa Farag

9 Mar 2021

PONE-D-20-19261R2

Pooled prevalence and associated factors of health facility delivery in East Africa: Mixed-effect logistic regression analysis

PLOS ONE

Dear Dr. Tesema ,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by Apr 23 2021 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:

  • A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: http://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols

We look forward to receiving your revised manuscript.

Kind regards,

Marwa Farag

Academic Editor

PLOS ONE

Journal Requirements:

Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice.

Additional Editor Comments (if provided):

The authors have addressed the major comments in the paper. However, there are a few issues that still need to be addressed:

1- There are still language errors in the document. Even the first few lines of the abstract have several errors and I am not sure what pocket studies mean?:

"Despite health facility delivery is identified as a key strategy for reducing

maternal and neonatal mortality, it less utilized in many African countries. There are

pocket studies on the prevalence and associated factors of health facility delivery in

different East African countries but the prevalence and significant factors were varied

from study to study."

"So, pooled analysis using the nationally representative DHS data of East African

114 countries is vital for understanding associated factors common across countries." Is an informal way to express this idea.

This paper MUST be reviewed by a professional editor.

2- The discussion about how the time dimension was handled also need to be included in the manuscript.

[Note: HTML markup is below. Please do not edit.]

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

PLoS One. 2021 Apr 23;16(4):e0250447. doi: 10.1371/journal.pone.0250447.r006

Author response to Decision Letter 2


12 Mar 2021

Point by point response for editors/reviewers comments

PLOS ONE Journal

Manuscript title: Pooled prevalence and associated factors of health facility delivery in East Africa: Mixed-effect logistic regression analysis

Manuscript ID: PONE-D-20-19261R2

Dear editor.

Dear all,

We would like to thank you for these constructive, building, and improvable comments on this manuscript that would improve the substance and content of the manuscript. We considered each comment and clarification questions of editors and reviewers on the manuscript thoroughly. Our point-by-point responses for each comment and question are described in detail on the following pages. Further, the details of changes were shown by track changes in the supplementary document attached.

Response to Editors’ comment

1. - There are still language errors in the document. Even the first few lines of the abstract have several errors and I am not sure what pocket studies mean?:

"Despite health facility delivery is identified as a key strategy for reducing

maternal and neonatal mortality, it less utilized in many African countries. There are

pocket studies on the prevalence and associated factors of health facility delivery in

different East African countries but the prevalence and significant factors were varied

from study to study." "So, pooled analysis using the nationally representative DHS data of East African 114 countries is vital for understanding associated factors common across countries." Is an informal way to express this idea.

Authors’ response: Thank you for the comments. We extensively modified the sentence structure and for any typographical error with the help of language experts at the university. (See the revised manuscript)

2. The discussion about how the time dimension was handled also need to be included in the manuscript.

Authors’ response: Thank you for the comments. We included in the method section. (See the revised manuscript)

Attachment

Submitted filename: Point by point response.docx

Decision Letter 3

Marwa Farag

16 Mar 2021

PONE-D-20-19261R3

Pooled prevalence and associated factors of health facility delivery in East Africa: Mixed-effect logistic regression analysis

PLOS ONE

Dear Dr. Tesema,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by Apr 30 2021 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:

  • A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: http://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols

We look forward to receiving your revised manuscript.

Kind regards,

Marwa Farag

Academic Editor

PLOS ONE

Journal Requirements:

Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice.

Additional Editor Comments (if provided):

There are still language errors even in the abstract:

Examples:

1- "This study showed that health facility delivery in East African countries is low." It should say the percentage or rate of health facility delivery)

2- "These findings suggested that maternal and child health programs should enhance health facility delivery in rural residents and poor households by enhancing maternal education, and ANC service utilization." This sentence is poorly written and hard to understand.

Please have the manuscript professionally edited. There are still errors even in the abstract.

[Note: HTML markup is below. Please do not edit.]

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

PLoS One. 2021 Apr 23;16(4):e0250447. doi: 10.1371/journal.pone.0250447.r008

Author response to Decision Letter 3


20 Mar 2021

Point by point response for editors/reviewers comments

PLOS ONE Journal

Manuscript title: Pooled prevalence and associated factors of health facility delivery in East Africa: Mixed-effect logistic regression analysis

Manuscript ID: PONE-D-20-19261R3

Dear editor.

Dear all,

We would like to thank you for these constructive, building, and improvable comments on this manuscript that would improve the substance and content of the manuscript. We considered each comment and clarification questions of editors on the manuscript thoroughly. Our point-by-point responses for each comment and question are described in detail on the following pages. Further, the details of changes were shown by track changes in the supplementary document attached.

Response to Editors’ comment

1. There are still language errors even in the abstract:

Examples:

1- "This study showed that health facility delivery in East African countries is low." It should say the percentage or rate of health facility delivery)

2- "These findings suggested that maternal and child health programs should enhance health facility delivery in rural residents and poor households by enhancing maternal education, and ANC service utilization." This sentence is poorly written and hard to understand.

Please have the manuscript professionally edited. There are still errors even in the abstract.

Authors’ response: Thank you Editor for the comments. We extensively edited the whole manuscript for any typographical and grammatical errors. Besides, it is reviewed by language experts at the university. (See the revised manuscript)

Attachment

Submitted filename: Point by point response.docx

Decision Letter 4

Marwa Farag

24 Mar 2021

PONE-D-20-19261R4

Pooled prevalence and associated factors of health facility delivery in East Africa: Mixed-effect logistic regression analysis

PLOS ONE

Dear Dr. Tesema,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by May 08 2021 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:

  • A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: http://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols

We look forward to receiving your revised manuscript.

Kind regards,

Marwa Farag

Academic Editor

PLOS ONE

Journal Requirements:

Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice.

Additional Editor Comments (if provided):

The language of the manuscript is still inadequate. The manuscript cannot be accepted in its current form.

There are still language errors - even in the abstract.

This is the conclusions section in the abstract of the paper:

Conclusion: This study showed that the proportion of health facility delivery in East African

countries is low.

*Clear 

'Country, residence, maternal education status, husband education status,

marital status, occupation status, wealth status, ANC visit, health care access, parity, type of

gestation and wanted pregnancy were significantly associated factors of health facility delivery.'

*This sentence is typically reported as part of the results and not conclusions section

Enhancing maternal education and ANC visit would increase delivery at a health facility. We

recommended maternal health programs targeting improving health facility delivery should emphasize for rural residents.

* You cannot say enhance ANC visit? what does this mean? Also would increase delivery at a health facility implies that you established causality, which is not the case so you should say likely to increase or expected to increase instead. 

* the sentence "We recommended maternal health programs targeting improving health facility delivery should emphasize for rural residents." is grammatically incorrect and poorly structured

[Note: HTML markup is below. Please do not edit.]

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

PLoS One. 2021 Apr 23;16(4):e0250447. doi: 10.1371/journal.pone.0250447.r010

Author response to Decision Letter 4


29 Mar 2021

PLOS ONE

Point by point response for editors comments

Manuscript title: Pooled prevalence and associated factors of health facility delivery in East Africa: Mixed-effect logistic regression analysis

Manuscript ID: PONE-D-20-19261R4

Dear editor/reviewer.

Dear all,

We would like to thank you for these constructive, building, and improvable comments on this manuscript that would improve the substance and content of the manuscript. We considered each comment on the manuscript thoroughly. Our point-by-point responses for each comment and question are described in detail on the following pages.

Response to Editors comment

1. Journal Requirements:

Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice.

Authors’ response: Thank you for the concerns. We assessed all the references cited in the manuscript and there is no retracted refrences.

2. The language of the manuscript is still inadequate. The manuscript cannot be accepted in its current form.

There are still language errors - even in the abstract.

This is the conclusions section in the abstract of the paper:

Conclusion: This study showed that the proportion of health facility delivery in East African

countries is low.

*Clear

'Country, residence, maternal education status, husband education status,

marital status, occupation status, wealth status, ANC visit, health care access, parity, type of

gestation and wanted pregnancy were significantly associated factors of health facility delivery.'

*This sentence is typically reported as part of the results and not conclusions section

Enhancing maternal education and ANC visit would increase delivery at a health facility. We

recommended maternal health programs targeting improving health facility delivery should emphasize for rural residents.

* You cannot say enhance ANC visit? what does this mean? Also would increase delivery at a health facility implies that you established causality, which is not the case so you should say likely to increase or expected to increase instead.

* the sentence "We recommended maternal health programs targeting improving health facility delivery should emphasize for rural residents." is grammatically incorrect and poorly structured

Authors’ response: Thank you for the commnets. We extensively edited and corrected the sentence structure with the help of language experts at the university. (See the revised manuscript)

Attachment

Submitted filename: Point by point response.docx

Decision Letter 5

Marwa Farag

7 Apr 2021

Pooled prevalence and associated factors of health facility delivery in East Africa: Mixed-effect logistic regression analysis

PONE-D-20-19261R5

Dear Dr. Tesema,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

An invoice for payment will follow shortly after the formal acceptance. To ensure an efficient process, please log into Editorial Manager at http://www.editorialmanager.com/pone/, click the 'Update My Information' link at the top of the page, and double check that your user information is up-to-date. If you have any billing related questions, please contact our Author Billing department directly at authorbilling@plos.org.

If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they’ll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org.

Kind regards,

Marwa Farag

Guest Editor

PLOS ONE

Additional Editor Comments (optional):

Reviewers' comments:

Acceptance letter

Marwa Farag

13 Apr 2021

PONE-D-20-19261R5

Pooled prevalence and associated factors of health facility delivery in East Africa: Mixed-effect logistic regression analysis

Dear Dr. Tesema:

I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS ONE. Congratulations! Your manuscript is now with our production department.

If your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information please contact onepress@plos.org.

If we can help with anything else, please email us at plosone@plos.org.

Thank you for submitting your work to PLOS ONE and supporting open access.

Kind regards,

PLOS ONE Editorial Office Staff

on behalf of

Dr. Marwa Farag

Guest Editor

PLOS ONE

Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    Attachment

    Submitted filename: review comments_healthfacility_PLosONE.docx

    Attachment

    Submitted filename: Point by point response.docx

    Attachment

    Submitted filename: Point by point response.docx

    Attachment

    Submitted filename: Point by point response.docx

    Attachment

    Submitted filename: Point by point response.docx

    Attachment

    Submitted filename: Point by point response.docx

    Data Availability Statement

    The underlying data is available online from www.measuredhs.com.


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