Figure 10.
ATR/ATM inhibition protects HeLa and T24 cells from the cytotoxic effects of 5-FU. HeLa (left panel) and T24 cells (right panel) were treated for 48 h with increasing concentrations of 5-FU and ATR/ATM inhibitors, either alone or in combination, as indicated. The number of viable cells was measured using an MTT assay. Viability is expressed as a percentage of the viability of untreated cells, which was set to 100 percent.