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. 2021 Mar 30;9(4):351. doi: 10.3390/biomedicines9040351

Figure 5.

Figure 5

A summary of human cytomegalovirus (HCMV) modulation of natural killer (NK) cell cytotoxicity discussed in this review. Human proteins or receptors are labelled in black; HCMV proteins are labelled in red. The arrows represent actions. Two-pointed solid black arrow = interaction or ligation; one-pointed solid black arrow = intracellular NK cell activation signal; dotted black arrow = intracellular NK cell inhibition signal; yellow arrow = extracellular signal to target cell; red line = inhibits surface expression; blue arrow = increases surface expression. Figure created with BioRender.com.