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The mean inhibition concentration 50 (IC50) values for EA.hy926 cells as a function of lipid, P407, PEI, DMAPAP, and siRNA content in the nanocarrier formulations (N/A: Not applicable).
| Cell Lines | Component | PLPEI | PvcLPEI | PLDMAPAP | PvcLDMAPAP |
|---|---|---|---|---|---|
| Endothelial Cells (IC50) | Lipid (mg/mL) | 2 | ˃2 | ˃2 | >5 |
| P407 (mg/mL) | N/A | 52 | N/A | >100 | |
| PEI (mg/mL) | 0.03 | 0.03 | N/A | N/A | |
| DMAPAP (mg/mL) | N/A | N/A | 0.21 | >1 |
