Table 2.
Name of Formulation | Loaded Substance | Concentration of Loaded Substance in SEDDS |
---|---|---|
DDAB-OND in SEDDS | Complex of DDAB and OND at the charge ratio 3:1 |
100 nmol of OND/g SEDDS |
DOTAP-OND in SEDDS | Complex of DOTAP and OND at the charge ratio 3:1 |
100 nmol of OND/g SEDDS |
DDAB in SEDDS | DDAB | 3.8 mg/g SEDDS |
DOTAP in SEDDS | DOTAP | 4.2 mg/g SEDDS |
SEDDS + Orlistat | Orlistat | 0.25%(w/w) |
DDAB: dimethyldioctadecylammonium bromide, DOTAP: 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) and OND: oligonucleotide.