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. 2021 Apr 6;10(4):816. doi: 10.3390/cells10040816

Figure 9.

Figure 9

Effects of inhibitors which target events involved in metastasis on the growth of MIA-PaCa-2 + WT-GSK-3β, MIA-PaCa-2 + KD-GSK-3β, and MIA-PaCa-2 + pLXSN cells. The effects of the galectin-1 inhibitor OTX008 (Panel (A)), the serpine-1 inhibitor tiplaxtinin (Panel (B)) and the Hh pathway inhibitor vismodegib (Panel (C)) on MIA-PaCa-2 + WT-GSK-3β (solid red boxes), MIA-PaCa-2 + KD-GSK-3β (solid blue triangles), and MIA-PaCa-2 + pLXSN Cells (solid green circles) were examined via MTT analysis. The MIA-PaCa-2 + WT-GSK-3β, MIA-PaCa-2 + KD-GSK-3β, and MIA-PaCa-2 + pLXSN cells in each panel were all examined at the same time period. These experiments were repeated 4 times and similar results were obtained. Statistical analyses were performed by the Student T test on the means and standard deviations of various treatment groups. ** p < 0.005, and NS = not statistically significant.