Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 7;11(4):226. doi: 10.3390/metabo11040226

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

DHEA (G6PD inhibitor) decreased the ¹³C enrichments of HUVEC glycolytic and TCA metabolites, as well as amino acids, R5P, and nucleotide precursors UMP and AMP. (a) Heatmap comparing ¹³C metabolite enrichment of untreated HUVECs and DHEA-treated HUVECs. ¹³C enrichment of (b) glycolytic metabolites, (c) TCA metabolites, (d) amino acids, (e) R5P, and (f) UMP, AMP, and UDP-glucose. Statistical significance for (b–f) determined through Welch’s unequal variances t-test; * p < 0.05; ** p < 0.01; *** p < 0.001, **** p < 0.0001. n = 6 biological replicates.