. 2021 Apr 19;26(8):2366. doi: 10.3390/molecules26082366

Table 7.

The anti-proliferative activity and selectivity index of compounds from Marynka hop variety.

Cell Line	Crude Extract (E1)		Xanthohumol (XN)
Cell Line	IC₅₀ ^a [μg/mL]	SI ^b	IC₅₀ ^a [μg/mL]	SI ^b
A549	45.17 ± 3.58	2.30	7.39 ± 2.99	2.33
HepG2	26.27 ± 1.56	3.97	36.36 ± 3.48	0.47
MCF-7	66.48 ± 2.97	1.56	12.18 ± 2.89	1.42
BJ	104.30 ± 4.16	-	17.25 ± 1.35	-

^a IC₅₀—concentration of compound required to inhibit cell proliferation to 50%. ^b SI- selective index. The value was calculated as a ratio between IC₅₀ for normal cells (BJ) and IC₅₀ for cancer cells (A549, HepG2 or MCF-7).