Figure 2:

Correlation between methylation clusters and important expression programs in osteosarcoma. Correlations between methylation summary values for each DNA methylation cluster and previously described expression programs were calculated for canine (A, n=9) and human (B, n=16) samples where methylation and expression data was available. Correlations were also calculated for additional phenotypic data for canine samples. Heatmaps indicate Pearson correlation values between each DNA methylation cluster and phenotype where red is strong positive correlation and blue is strong negative correlation. Color bars next to module names indicate pathway analysis results and are the same as in the previous figure. HG = human GCESS, CG = canine GCESS from Scott et al 2018⁸.