Table 5. Metformin concentration in the plasma, breast muscle (right M. pectoralis major), and liver of layer and broiler chickens fed a diet with various metformin concentrations.
| Experiment 1 (Layer) |
Experiment 2 (Broiler) |
|||
|---|---|---|---|---|
| Metformin (mg/kg) |
Plasma (µmol/L) |
Breast muscle (nmol/g tissue) |
Plasma (µmol/L) |
Breast muscle (nmol/g tissue) |
| 0 | 0.0±0.0c | 0.0±0.0b | 0.0±0.0b | 0.0±0.0b |
| 150 | 0.9±0.0b | 1.8±0.8a | 17.9±7.0ab | 0.8±0.3b |
| 300 | 1.7±0.0a | 2.0±0.6a | 35.2±8.4a | 1.7±0.3a |
a–c
Means in the same column not sharinga common superscript letter were significantly different (Tukey's HSD test, P<0.05). Values are given as mean±SE. The number of chickens used in each treatment group was 8.