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Oxford University Press - PMC COVID-19 Collection logoLink to Oxford University Press - PMC COVID-19 Collection
. 2021 Mar 26:ciab263. doi: 10.1093/cid/ciab263

Single dose of a mRNA SARS-CoV-2 vaccine is associated with lower nasopharyngeal viral load among nursing home residents with asymptomatic COVID-19

M Catherine McEllistrem 1,, Cornelius J Clancy 1,2, Deanna J Buehrle 1, Aaron Lucas 1,2, Brooke K Decker 1,2
PMCID: PMC8083695  PMID: 33768222

Abstract

In nursing home residents with asymptomatic COVID-19 diagnosed through twice-weekly surveillance testing, single dose BNT162b2 vaccination (Pfizer-BioNTech) was associated with -2.4 mean log10 lower nasopharyngeal viral load than detected in absence of vaccination (p=0.004). Since viral load is linked to transmission, single dose mRNA SARS-CoV-2 vaccination may help control outbreaks.

Keywords: SARS-CoV-2, COVID-19, Viral Load, Cycle Threshold, Asymptomatic


Articles from Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America are provided here courtesy of Oxford University Press

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