Self-Regulation and Shame as Mediators Between Childhood Experiences and Young Adult Health

Abstract

The purpose of this study was to determine whether self-regulation and shame mediated the relationship between adverse and positive childhood experiences (ACEs and PCEs) and young adult health. Data came from the Flourishing Families Project (FFP), a 10-year longitudinal study. Adolescent participants (N = 489; 51% female) completed an annual survey. Data were analyzed using structural equation modeling. Results indicated that PCEs negatively predicted shame and positively predicted self-regulation while ACEs negatively predicted self-regulation. Shame mediated the relationship between PCEs and depression. Self-regulation mediated the relationship between both ACEs and PCEs with anxiety; self-regulation also mediated the relationship between ACEs and substance abuse. Childhood experiences appear to affect the development and maintenance of self-regulation in adolescence. Self-regulation appears to be especially important in protecting against depression, anxiety, and substance abuse in young adulthood.

Introduction

Adverse childhood experiences, or ACEs, are potentially traumatic and stressful events that occur before the age of 18 such as emotional, physical, or sexual abuse, and household dysfunction (e.g., parental depression, incarceration of a family member, family member using illicit drugs) (1). ACEs are associated with negative health behaviors and outcomes such as alcohol use, smoking, and depression (1–3). Conversely, cumulative scores of advantageous factors known as positive childhood experiences (PCEs; also referred to as advantageous childhood experiences and benevolent childhood experiences in the literature) are associated with lower depression and stress and better positive psychology, irrespective of ACE scores (4). PCEs include healthy relationships with others such as feeling safe with at least one parent, having good neighbors, feeling like one's teachers care about them, and having at least one good friend. In the absence of these positive relationships, higher levels of distress have been reported among youth (5), but when present, PCEs may attenuate the negative effects of ACEs on health (4, 6–9).

In the current study, we examined the role of two potential mediators, self-regulation and shame. These mediators were selected because their healthy development may be influenced by childhood experiences that occur during adolescence and they are known to be associated with adult psychopathology (10, 11). Self-regulation is the ability to engage in goal-directed behavior through controlling one's behaviors, emotions, and thoughts (12). Some research has shown that shame is an aspect of emotional self-regulation; shame has been defined as a family of emotions such as embarrassment, inferiority, and humiliation that one has internalized that are the result of others' negative evaluations (13, 14).

Childhood Experiences and Young Adult Mental Health

A growing number of studies indicate that ACEs experienced during the first 18 years of life increase mental health problems in young adulthood. For example, one study comprised from a British cohort born during a 1-week period in 1958 in England, Scotland, and Wales found that ACEs (measured at ages 7, 11, and 16) predicted worse young adult mental health (15). Among 239 college students, with a mean age of 20 years old, from a large public university in the Midwest, ACEs that occurred before age 18 years predicted increased likelihood of developing depression or an anxiety disorder over the duration of the semester (16). Another study of 1,578 high school seniors from nine Boston Metropolitan area public schools found that cumulative adversity resulted in disproportionately worse mental health in young adulthood based on participant lifetime reporting (17). Similarly, a study comprised 1,142 participants of the Chicago Longitudinal Study (CLS) aged 22–24 found that ACEs scores were related to poorer self-rated health and more depressive symptoms and substance abuse in early adulthood (18).

Fewer studies have examined the relationship between PCEs and young adult health. Of the studies that have investigated this relationship, the majority have focused on individual positive experiences rather than cumulative PCE scores. For example, prior research has shown that positive relationships such as the parent-child relationship lead to the development of better cognitive and emotional development (19, 20). However, taken together these studies indicate that PCEs protect against psychological stress in early and later adulthood (7, 21).

Some research suggests that experiences in adolescence could be more predictive of young adult health than positive and adverse experiences that occurred in early or middle childhood (22). However, most research examining the effects of ACEs on young adult health has examined childhood experiences that occurred between birth and age 18 years. Research examining ACEs and PCEs at specific points during childhood and adolescence is important to better understand the relative impact of these experiences at each stage on child and youth development. Furthermore, there is a need for studies that explain the mechanisms through which childhood experiences affect lifelong health.

The Effects of Adverse and Positive Experiences on Adolescent Development

Adolescence and young adulthood are important to study because adolescence is an important period for social and cognitive development (23), and this development continues into young adulthood when individuals undergo key life transitions such as leaving home, entering the workforce, beginning college, or getting married. Given all these major life transitions, mental health issues often begin in late adolescence and young adulthood (24). Adolescence is a key sensitive period for the development of the prefrontal cortex, which develops over the first three decades of life (25, 26). The brain's prefrontal cortex governs, in part, self-regulation, and shame (27). Due to the protracted development of the prefrontal cortex, proximal environmental factors such as family experiences during adolescence play a key role in the healthy development of self-regulation and shame (28). ACEs and PCEs in adolescence may affect the structure and function of the brain as well as neural communication between different parts of the brain associated with self-regulation and shame (25, 29, 30). Brain imaging studies indicate that ACEs may negatively affect the development and structure of the prefrontal cortex, hippocampus, amygdala, and other parts of the brain that are important to self-regulation and emotion, whereas PCEs, such as positive parenting, promote more normative brain development even in the face of ACEs (20, 31).

Self-Regulation and Shame as Potential Mediators Between Childhood Experiences and Young Adult Health

In the context of this study, if an individual is exposed to forms of abuse or maltreatment in adolescence, the development of their self-regulatory skills and shame management could be poorly impacted. Higher shame and impaired self-regulatory skills may negatively affect young adult capacity and confidence to manage life's challenges and early symptoms of psychopathology, and possibly lead to unhealthy coping mechanisms such as substance abuse. On the other hand, if an individual experiences a variety of positive experiences, this could enhance the development of self-regulation and reduce internalizing of unhealthy emotions associated with shame. Well-developed self-regulatory capacities provide tools to aid in key life changes occurring in young adulthood, leading to more fulfilling experiences in young adulthood that may help to combat substance abuse and symptoms associated with anxiety and depression (32, 33). In fact, individuals who experience a high number of PCEs may be able to overcome the negative effects of adversity, yielding better mental health as young adults regardless of ACEs score (31, 34).

Existing research lends support for this framework and suggests that self-regulation and shame may mediate the relationship between ACEs and PCEs with young adult mental health. Higher ACE scores have been linked to worse self-regulation during adolescence (35), while higher PCEs are associated with better self-regulation (4). Better self-regulation leads to less depressive symptoms, even in the presence of ACEs (36, 37). As it relates to shame, exposure to childhood trauma has been associated with increased shame in multiple adolescent populations (38–40), leading to higher rates of depression in young adulthood (41, 42).

Aims and Hypotheses

Extant literature indicates that childhood experiences affect self-regulation and shame (42), and that self-regulation (43) and shame (44) affect later health. However, most prior studies have been cross-sectional and to our knowledge research has not yet examined shame and self-regulation as mediators between childhood experiences with young adult health. Understanding the mechanisms through which childhood experiences that occur during adolescence affect later health may be important to developing more effective interventions. Furthermore, few studies have examined both ACEs and PCEs in the same model as predictors of young adult health. The purpose of this study was to address this gap in the literature by examining the potential mediating pathways of shame and self-regulation between both PCEs and ACEs on young adult mental health. We hypothesized that both shame and self-regulation would mediate the relationship between ACEs and PCEs with depression, anxiety, and substance abuse. Specifically, we predicted that (1) ACEs would decrease self-regulation and increase shame, (2) PCEs would increase self-regulation and decrease shame, (3) higher self-regulation would protect against poor mental health, and (4) greater shame would increase poor mental health.

Methods

Sample and Procedures

The data for this study came from the Flourishing Families Project (FFP), a 10-year longitudinal study with annual follow-ups that took place in a large city in the Northwestern United States. The FFP was approved by the university Institutional Review Board (IRB). Baseline data were collected among 500 adolescents and their parents in 2007, when adolescents were between the ages of 10 and 13 years. Participants were initially recruited from the Polk Directory National Database, a registry based on telephone, magazine, and internet subscriptions. As participants did not proportionally represent those of lower socioeconomic statuses, an additional low-income sample was recruited via referrals and fliers, resulting in a sample more representative of local zip codes.

In each wave (spaced 1 year apart), adolescents and their parents completed a survey. Data for waves 1–5 were collected through home surveying; as participants transitioned into adulthood, in waves 6–10 the survey was administered online. Retention was high across waves, with 87.6% of the sample participating in wave 10. As a result of some missing demographic information, data from 489 of the original 500 adolescents and their parents were used in the current study.

Measures

Independent Variables: Childhood Experiences

An ACE questionnaire was not included in the FFP. However, items that fit the criteria of an ACE were adapted to create an ACEs measure, which has been further described elsewhere (7). A total of eight ACEs were included: poverty (parent report), mental illness in one or both parents (parent report), substance abuse in the household (adolescent report), incarcerated household member (adolescent report), parental separation or divorce (parent report), interparental conflict (adolescent report), child physical punishment (adolescent report), and child emotional abuse (adolescent report). Items were reported in waves 1–5 when adolescents were ~13–18 years. Some ACEs were based on a single item (e.g., parent trouble with the law—reports of sometimes or higher were coded as an ACE) while other ACEs were based on a scale or questionnaire (e.g., Center for Epidemiologic Studies Depression Scale to measure parental depression; average score of sometimes or higher were coded as an ACE). If the ACE occurred in any wave, it was coded as a one for being present. If the ACE did not occur in any wave, it was coded as zero. The scores were summed for a cumulative ACE score ranging from 0 to 8.

A PCE questionnaire was also not included in the FFP. However, items that fit the criteria of a PCE were used to create a PCE score (7). A total of 10 PCEs were included including adolescent report of parent child connection, parent report of parental monitoring, having at least one good friend (adolescent report), having beliefs that gave you comfort (adolescent report), liking school (adolescent report), having at least one teacher who cares about you (adolescent report), having good neighbors (parent report), having opportunities to have a good time (adolescent report), liking or feeling comfortable with yourself (adolescent report), and having a predictable home routine that included things like a regular bedtime and meals (parent report). Some PCEs were based on single items in the survey (e.g., agreement or strong agreement with the statement “I feel happy in school”) and others were based on a survey scale (e.g., Rosenberg Self-Esteem scale, with average scores indicating agreement or higher marked as a PCE). If a PCE occurred in any wave, it was coded as one for being present. If the PCE did not occur in any wave, it was coded as zero. The scores were summed for a total PCE score ranging from 0 to 10.

Mediating Variables: Self-Regulation and Shame

Self-regulation was measured in wave 7 from a self-regulation scale developed by Novak and Clayton (45). The 13-item scale included response options ranging from 1 = never true to 4 = always true. The scale is composed of behavioral, emotional, and cognitive self-regulation subscales, but only subscales for behavioral and emotional self-regulation were used in the current study. Sample items included: “I get distracted by little things” and “I have a hard time controlling my temper.” Self-regulation was calculated based on both adolescent self-report and parent report of adolescent self-regulation. To facilitate parent report about their child, the items were adapted (e.g., “My child gets distracted by little things.”). Each subscale was summed and averaged for each reporter, resulting in six subscale scores. The Cronbach's alphas for each subscale and reporter ranged from 0.75 to 0.90. Prior studies using the self-regulation scale among children only found Cronbach's alphas >0.90 (45). Prior studies have examined the factor structure of self-regulation combining parent and child report and have found good fit in confirmatory factor analysis (46).

Shame was measured in wave 7 via adolescent self-report using the 8-item Shame Profile Scale (47). Response options were on a 5-point Likert Scale ranging from 1 = never to 5 = almost always, with higher scores indicating greater shame. Sample items included: “I feel like I am never quite good enough” and “I think that people look down on me.” The Cronbach's alpha for the current study was 0.96, which is higher than reliabilities from prior studies ranging from 0.75 to 0.80 (47).

Dependent Variables: Mental Health Indicators

The self-reported mental health indicators of depression, anxiety, and substance abuse were measured in wave 10 when participants were between 20 and 23 years. Depression was measured using the 20-item Center for Epidemiological Studies Depression Scale for Children (48), and had a Cronbach's alpha of 0.92 in the current sample. Response options ranged from 1 = not at all to 4 = a lot. Higher scores indicated more depressive symptoms. Sample items included: “I felt down and unhappy” and “I felt like I was too tired to do things.”

Higher scores on the Spence Child Anxiety Inventory (49), a 6-item scale with a Cronbach's alpha of 0.89 in the current study, indicated greater anxiety among participants. Response options were on a 4-point scale, ranging from 0 = never to 3 = always. Sample items included: “When I have a problem, my heart beats really fast” and “I worry that something bad will happen to me.”

The Adolescent Alcohol and Drug Involvement Scale (50) was used to measure substance abuse. The 6-item scale had a Cronbach's alpha of 0.80 in the current sample. Because most of the participants could legally drink alcohol in wave 10, alcohol use was excluded. The frequency of use of marijuana, tobacco, other illegal drugs, legal drugs without a prescription, and binge drinking were measured with an 8-point Likert scale, ranging from never to several times a day. Due to low counts on some responses, categorization of binge drinking was 0 = never, 1 = several times a year, and 2 = monthly or more. Categorization of other substances was 0 = never used, 1 = tried but quit, and 2 = currently use.

Control Variables

Because there were socioeconomic differences in sampling methodology, we controlled for sampling (1 = Polk sample; 0 = convenience sampling) in our models. Adolescent gender, age in years at baseline, and race were also included as control variables in the final models. Gender was measured as 1 = male and 2 = female among adolescents. Race was coded as 0 = other race; 1 = Black/African American race; 2 = multi-racial; 3 = Asian; 4 = non-Hispanic White. Race was included as a covariate because prior studies have indicated that non-Hispanic Whites and Asians have lower risk for ACEs as compared to African Americans and other minority races (51, 52).

Statistical Analysis

Data were analyzed in Mplus version 7. A measurement model was established by conducting confirmatory factor analysis (CFA) to create latent variables for the three outcome constructs (depression, anxiety, and substance abuse) and the two mediators (self-regulation and shame). Items with factor loadings <0.40 were dropped. Both parent and adolescent-report of cognitive self-regulation were dropped due to low loadings as was parent report of adolescent behavioral self-regulation. Model fit for the final measurement model was adequate (RMSEA = 0.05; CFI = 0.95).

A structural equation model (SEM) was fit by regressing the three mental health outcomes on shame, self-regulation, ACEs, and PCEs. Shame and self-regulation were also regressed on ACEs and PCEs. Next, the control variables were added by regressing the outcome, mediating, and independent variables on the controls. To ensure robust standard errors, we used 5,000 bootstraps to test the significance of indirect effects (53).

All models were estimated using variance-adjusted weighted least squares approximation, which is appropriate for categorical data. Missing data were minimal and were accounted for in Mplus using Full Information Maximum Likelihood (FIML). For both the measurement and structural model, model fit was determined based on the Root Mean Square Error of Approximation (RMSEA; values <0.08 indicated adequate fit) and Comparative Fit Index (CFI; values >0.90 indicated adequate fit) (54).

Results

Demographics

On average, adolescents were 11.3 years old at age baseline, with 51% of participants who reported their gender as female and 49% reported male. Reported race distribution was as follows: 69.7% non-Hispanic White, 12.9% as African American or Black, 11.2% as multi-racial, 3.9% as Asian, and 2.3% as other race. The average ACE score for adolescents was 2.7, and the average PCE score was 8.2. Table 1 includes a correlation matrix of all model variables.

Table 1.

Correlation matrix, N = 489.

	ACE	PCE	Self-regulation	Shame	Depression	Anxiety	Substance abuse	Age at baseline	Race	Gender	Sampling method
ACE	1.000
PCE	−0.255***	1.000
Self-regulation	−0.265***	0.256***	1.000
Shame	0.054	−0.190***	−0.648***	1.000
Depression	0.116*	−0.120*	−0.457***	0.474***	1.000
Anxiety	0.110*	−0.100*	−0.511***	0.379***	0.575***	1.000
Substance abuse	0.072	−0.120*	−0.173**	0.071	0.104	0.102	1.000
Age at baseline	0.171***	−0.155***	0.143**	−0.041	−0.080	−0.062	0.043	1.000
Race	−0.389***	0.198***	0.130*	0.040	−0.018	−0.035	0.093	−0.089	1.000
Gender	0.015	−0.006	−0.242***	−0.207***	0.196***	0.315***	−0.198***	−0.033	−0.030	1.000
Sampling method	0.225***	−0.023	0.084	−0.094*	−0.017	−0.072	−0.084	0.080	−0.372***	−0.057	1.000

^*p < 0.05.

^**p < 0.01.

^***p < 0.001.

For gender, 0 = male, 1 = female.

Self-Regulation and Shame as Mediators Between Childhood Experiences and Young Adult Mental Health

Table 2 contains the structural equation modeling results for the role of childhood experiences on shame, self-regulation, and young adult mental health (Figure 1 provides the standardized results of the final model with significant paths only shown). Neither ACEs nor PCEs directly predicted any of the young adult mental health outcomes. PCEs negatively predicted shame and positively predicted self-regulation. ACEs did not predict shame but were negatively associated with self-regulation. Shame predicted more depression but was not associated with anxiety or substance abuse. Self-regulation predicted less depression, anxiety, and substance abuse.

Table 2.

Structural equation model results for the role of childhood experiences on shame, self-regulation, and young adult mental health (N = 489; model fit: RMSEA = 0.049; CFI = 0.946).

	Shame	Self-regulation	Depression	Anxiety	Substance abuse
ACEs	0.038	−0.235***	0.042	−0.001	0.028
PCEs	−0.204***	0.208***	0.003	0.003	−0.075
Shame	–	–	0.311***	0.066	−0.098
Self-Regulation	–	–	−0.223*	−0.419***	−0.312**

^*p < 0.05.

^**p < 0.01.

^***p < 0.001.

Model controls for adolescent race, gender, age at baseline, and sampling method. Coefficients are standardized.

Figure 1.

Structural equation model for the role of childhood experiences oh shame, self-regulation, and young adult mental health, N = 489. *p < 0.05. **p < 0.01. ***p < 0.001. Model fit: RMSEA = 0.049; CFI = 0.946. Model controls for adolescent race, gender, age at baseline, and sampling method. Path coefficients are standardized. Only significant paths are shown.

Table 3 shows the significant mediating pathways based on 5,000 bootstrap computations. Shame partially mediated the relationship between PCEs and depression. Self-regulation partially mediated the relationship between both ACEs and PCEs with anxiety. Self-regulation also partially mediated the relationship between ACEs and substance abuse. No other mediating pathways were significant.

Table 3.

Results of significant paths for shame and self-regulation as mediators.

Significant indirect pathways	Z-score
PCEs > shame > depression	−3.011**
PCEs > self-regulation > anxiety	−2.530*
ACEs > self-regulation > anxiety	2.788**
ACEs > self-regulation > substance abuse	2.202*

^*p < 0.05.

^**p < 0.01.

Discussion

The purpose of this study was to determine whether self-regulation and shame mediated the relationship between ACEs and PCEs with young adult mental health. Prior research has indicated that higher ACE scores lead to worse self-rated health, more prevalent depressive symptoms, and substance abuse (18). However, less is understood about the mechanisms through which childhood experiences affect young adult health. We hypothesized that childhood experiences would work through shame and self-regulation to affect young adult mental health. The results of this study largely confirmed our hypothesis. Both ACEs and PCEs predicted self-regulation in the expected direction, with self-regulation mediating the relationships between both ACEs and PCEs with anxiety and between ACEs and substance abuse. PCEs but not ACEs predicted shame, and shame mediated the relationship between PCEs and depression.

The results of the study are consistent with extant literature relating to how childhood experiences may affect the development of shame, self-regulation, and later mental health. Shame and self-regulation are developing at the same time as the occurrence of many key positive and adverse adolescent experiences. One explanation for why ACEs were predictive of worse self-regulation and PCEs were associated with less shame and better self-regulation is that cumulative adversity or advantage during adolescence may affect the connections made by neurons in the brain (30), thereby affecting self-regulatory skills and expressions of shame. Our findings are consistent with cognitive science (22, 55) that indicates that ACEs impact the brain's structure including the growth of the prefrontal cortex, hippocampus, amygdala, and the superior parietal region of the brain (20, 31). Conversely, individual PCEs such as positive parenting have been shown to promote healthier development of the amygdala and prefrontal cortex, especially in the face of adversity (20, 31). Because PCEs promote healthy brain development, individuals with high PCEs appear to have stronger self-regulation and less shame, leading them to more effectively control their thoughts, behaviors, and emotions, leading to better health in adulthood including lower rates of mental illness and less substance use.

Beyond cognitive science, discussion regarding how self-regulation and shame may affect later mental health is merited. Given the key life transitions happening in young adulthood and the increase in stressors as young adults juggle new life demands, shame and self-regulatory skills may be particularly important to managing mental health. In the current study, shame was predictive of more depression only while self-regulation was associated with less depression, anxiety, and substance abuse. Shame is inclusive of a range of negative self-appraisals that give way to more acute negative feelings such as self-contempt that have been widely associated with increased depression and anxiety symptoms (10). Surprisingly, we did not find an association between shame and anxiety. This may have been due, in part, to the greater relative importance of self-regulation. As self-regulation involves controlling emotions, behaviors, and cognitions, deficits in self-control mean lower levels of self-control and higher levels of impulsivity that have been linked with riskier behaviors such as substance use, particularly among individuals with a history of experiencing maltreatment (11). Self-regulatory capacities are not just important to externalizing behaviors such as substance use, but they are also important in helping individuals to regulate their emotions and cognitions, including cognitive distortions that are associated with psychopathology (56). Thus, considerations of self-regulation may be particularly important when examining how childhood experiences affect later mental health.

It is noteworthy that in pairwise correlations in the current study, PCEs were more strongly associated with both self-regulation and shame than were ACEs. Additionally, in the final models, PCEs were associated with depression through shame while ACEs had no direct nor indirect effect on depression. However, ACEs, but not PCEs, were indirectly associated with substance use. Thus, PCEs may have a greater impact on internalizing symptoms such as depression in young adulthood as compared to ACEs. However, externalizing symptoms such as substance abuse may be a way for individuals with ACEs to cope with the trauma that they have experienced.

Implications for Practice

These findings have important implications for practice. Preventing ACEs should always be a goal in public health. However, given the high prevalence of some ACEs (e.g., mental health in parents and parental separation and divorce) it is not feasible to always prevent ACEs. Therefore, consideration should also be given to increasing children's PCEs, which may be important to the development and maintenance of cognitive capacities such as the regulation of emotion and behaviors, which improve lifelong health (57). Programs designed to promote mindfulness and self-compassion may help to reduce shame (58). Several interventions have been successful at increasing self-regulation through enhancing positive experiences during middle childhood and adolescence (59). For example, the Family Check-Up has been found to increase youth's self-regulation, leading to less substance abuse, depression, and behavioral problems and better school engagement among youth (60, 61). Similarly, the Student Success Skills Program has been found to improve self-regulation in school settings (62).

Strengths and Limitations

A few limitations in the current student are important to note. We used proxy measures of ACEs and PCEs that have been used in prior research [e.g., see (7)] and closely match the questions in traditional ACEs and PCEs scales. Even though the concepts matched, caution is warranted when comparing results to studies that used actual ACE and PCE scales. We also used shame as a general measure and did not use a specify type such as internal or external shame. Our lack of a relationship between ACEs and shame may have been due to the lack of specificity in our shame measure. Furthermore, a more focused shame measure may help to lend better specificity of the shame mechanism through which childhood experiences affect later health. Thus, further research examining different aspects of shame is warranted. The Flourishing Families Project was focused on adolescent participants and we were unable to assess ACEs and PCEs that occurred before adolescence. Our results do highlight the effects of childhood experiences that occur during adolescence on self-regulation and shame, which is an important development period to understand. ACEs and PCEs experienced in early or middle childhood may affect brain development in different ways. Thus, the mechanisms through which childhood experiences that occur in early/middle childhood affect young adult health may be different from what was found in our study. Additionally, we did not have data on shame, self-regulation, or the mental health outcomes before adolescence, and the temporality of associations in our final model are not definitive.

Despite these limitations, this study has several strengths. Generally, surveys that measure ACEs and PCEs are administered in adulthood, years after the events have occurred, thereby resulting in recall bias of childhood experiences. In the current study, adolescents reported on their experiences each year, which decreased the likelihood of recall bias. Additionally, some measures included multiple reporters (e.g., parents and adolescents self-report), which increased the robustness of those measures. This study addresses a gap in the literature by examining the mechanisms through which both adverse and advantageous experiences affect health during a sensitive period of social and cognitive development (adolescence) using data from a 10-year longitudinal study.

Conclusion

Prior research has indicated a link between ACEs and worse adult health (1, 2) as well as between PCEs and better adult health outcomes (4, 6). Less is known about the mechanisms through which childhood experiences that occur specifically in adolescence affect young adult mental health. The current study indicates that ACEs may predict lower self-regulation, leading to more depression and anxiety symptoms and more substance abuse. Conversely, even in the presence of ACEs, PCEs experienced during adolescence are predictive of better self-regulation and less shame, leading to less depression and anxiety in young adulthood. Self-regulation and shame are both mechanisms through which childhood experiences may affect young adult depression, anxiety, and substance abuse, though self-regulation in particular appears to be especially salient to young adult mental health.

Data Availability Statement

The data analyzed in this study is subject to the following licenses/restrictions: Data may be available upon request from the corresponding author and a proposal to the Flourishing Families Project principal investigators. Requests to access these datasets should be directed to ali_crandall@byu.edu.

Ethics Statement

The Flourishing Families Project was approved by the Brigham Young University Institutional Review Board. Participants provided informed consent to participate.

Author Contributions

ER and AC conceptualized the study. AC analyzed the data, wrote the statistical methods, and edited the entire manuscript. ER wrote the manuscript. All authors contributed to the article and approved the submitted version.

Conflict of Interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.